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Akimba mice, a model of human diabetic retinopathy

Diabetic retinopathy (DR) is a major complication of diabetes and a growing problem as the systemic disease becomes more prevalent. DR develops insidiously from an asymptomatic form through to vascular damage that leads to oedema and breakdown of the blood-retinal...

What's trending Oct/Nov 2025

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #AlienEarth #TheEye One of the best shows to recently start streaming is, in my opinion, Alien: Earth. The cosmic horror of...

Comparing tensile strengths of two scleral fixated intraocular lenses: CT-Lucia and MA60

The authors designed a benchtop model to measure the tensile strengths and resistance to breakage of the haptics and haptic-optic junctions of the CT Lucia 602 (Carl Zeiss, California) and AcrySof MA60 (Alcon Laboratories, Texas) IOLs. For the haptic breakage...

Game show freak

As a child of the 70s and 80s, there were limited television viewing opportunities. For the duration of the 70s there were only three channels, only moving to four with the launch of Channel 4 in 1982. Not only that,...

Eyes on the road – visual standards for car drivers

The author examines the current visual standards required by drivers and asks whether more needs to be done to make roads safer. Are the public adequately protected by the current system of visual standards required by drivers? In a survey...

Thyroid eye disease

Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....

DMEK versus DSAEK

This systematic review and meta-analysis reviewed published evidence comparing two endothelial corneal transplants techniques; Descemet membrane endothelial keratoplasty (DMEK) and Descemet stripping automated endothelial keratoplasty (DSEAK). DMEK involves transplanting Descemet membrane with endothelial cells without any overlying stroma. In DSAEK...

Femto-DMEK – a solution for high re-bubbling rates?

This retrospective study examined results of patients that underwent femtosecond laser enabled descemet membrane endothelial keratoplasty (DMEK) (FE-DMEK) and manual DMEK (M-DMEK) for Fuch’s endothelial dystrophy. In FE-DMEK femtosecond laser was used to create 8.25mm descemetorhexis, whereas during M-DMEK- descemetorhexis...

DSEK – five year results

This UK based study examined long-term descemet stripping endothelial keratoplasty (DSEK) results, looking at graft survival and endothelial cell losses. Data on 210 grafts were included in analysis. Most frequent indication for DSEK was Fuch’s endothelial dystrophy (81.4%) and 46.3%...

Macular thickness and visual fields

The authors describe a comparison of spectral domain OCT with Humphrey visual fields (HVF) mean deviation (MD) and pattern standard deviation (PSD), examining the retinal thickness of the macula and circumpapillary retinal nerve fibre layer (RNFL) defects. Seventy-three subjects who...

The Arclight: A ‘pocket’ ophthalmoscope to revitalise undergraduate teaching?

Ophthalmoscopy should be a core skill for every doctor and should be firmly embedded in the undergraduate curriculum similar to the unquestioned position of the stethoscope. The simplicity of the Arclight means it is easy to useand, importantly, to learn...

Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...