You searched for "glaucoma"
RPTP-σ increases pro-MMP activity in a trabecular meshwork cell line following oxidative stress conditions
This study aims to outline the role of phosphatases in the aqueous drainage system by overexpressing receptor tyrosine phosphatase sigma (RPTP-σ) in a human normal trabecular meshwork cell line and describing its effect on subtypes of matrix metalloproteinases (MMP) and...
PD-1 and retinal ganglion cell death
Death of retinal ganglion cells (RGC) in conditions like glaucoma leads to permanent visual loss. RGC death can be due to the initial stress such as raised intraocular pressure or secondary to mechanism such as oxidative stress. Programmed cell death-1...
Same day air bubble removal after DSEK/DSAEK
A complete air removal on same day as descemet’s stripping endothelial keratoplasty (DSEK/DSAEK) leads to prompt restoration of the anterior chamber and thus has been hypothesised to assist with the recovery of endothelial function and promote graft adhesion. The results...
Effectiveness of Eagles Eye Mobile
The EEM programme was created to target children failing school nurse screening and likely to not have access to eye care. The EEM visits schools in low income areas providing optometric examinations to detect correctable refractive error, prescribe and deliver...
Optic nerve head perfusion response to reduced blood pressure and increased intraocular pressure
The purpose of this prospective study was to test the hypothesis that blood flow autoregulation in the optic nerve head has less reserve to maintain normal blood flow where there is a blood pressure induced decrease in ocular perfusion pressure...
Burden of caregiving for children with eye diseases
This review was conducted to examine the existent literature and characterise the psychological impact of caregiving for children with various eye diseases. The factors associated with the burden of caregiving were discussed in the context of each eye disease identified....
Changes in C:D ratio of premature infants with enlarged C:D ratios
This retrospective observational study examined the longitudinal alterations in cup to disc ratio (CDR) among premature infants exhibiting enlarged CDR and normal intraocular pressure (IOP) up to two years. Among the 283 infants, 13.4% manifested an enlarged CDR. In this...
Top cited 100 publications in paediatric ophthalmology
The author identified the top 100 cited publications in paediatric ophthalmology in an effort to identify which topics are most strongly represented and potential areas where further research is needed. An ISI Web of Science database search was conducted in...
Functional visual field loss using automated static perimetry
Functional visual field loss is traditionally assessed by kinetic perimetry, typically producing spiralling isopters. This study looked at the spatial distributions of functional field deficits using automated static perimetry. A retrospective review of automated perimetry records was conducted using a...
Neurotrophic keratitis
The authors present an overview of the aetiology, diagnosis, current and future management options of neurotrophic keratitis. This is a degenerative corneal disease that occurs following the compromise of trigeminal innervation, leading to hypoesthesia and / or anaesthesia. The aetiology...
Brimonidine day and night time IOP
The authors describe a randomised double masked study of 29 participants with ocular hypertension (OHT) who either self-administered 0.2% brimonidine or placebo three times daily for six weeks. Patients were seen during day time and night time visits and had...
