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Type 3 CNV and anti-VEGF

The purpose of the study was to determine the differences between aflibercept and ranibizumab in terms of their therapeutic efficacy in the treatment of Type 3 neovascularisation. The authors highlight that the dominant mechanism for Type 3 neovascularisation development is...

OCTA and pigment epithelium detachments

Yannuzzi et al. report on their study aiming to evaluate the ability of optical coherence tomography angiography (OCTA) to differentiate vascularised from nonvascularised pigment epithelium detachments (PEDs) using conventional imaging techniques, including fundus fluorescein angiography (FFA) and indocyanine green (ICG),...

Subfoveal choroidal thickness and PCV

This report studies the prognostic factors for visual improvement and the need for additional treatments at one year after the initial combination therapy of intravitreal ranibizumab injection or intravitreal aflibercept injection followed by PDT in eyes with PCV. Fifty-six eyes...

Systemic pharmacology of intravitreal anti-VEGF

This study aimed to evaluate and compare serum drug concentrations and plasma free-VEGF concentrations in patients with AMD, DME, or RVO receiving intravitreal injections of aflibercept, bevacizumab or ranibizumab. This prospective study enrolled patients from several offices of a single...

Macular hole postop positioning

The purpose of this study was to determine whether the full thickness macular hole (FTMH) closure rate with nonsupine positioning (NSP) is noninferior to the high closure rate achievable with face down positioning (FDP). All patients were pseudophakic pre macular...

Smartphone ophthalmoscopy vs. slit-lamp biomicroscopy in diabetic retinopathy

In this prospective, comparative, clinical study the authors’ aim was to assess the reliability and accuracy of smartphone ophthalmoscopy as compared with standard slit-lamp biomicroscopy in the grading of diabetic retinopathy. One hundred and twenty consecutive, new, diabetic patients underwent...

OCT positioning regimen in macular hole surgery

The authors set out to evaluate an OCT-based positioning regimen for macular hole surgery. Patients were advised to maintain prone positioning until the hole was confirmed to be closed based on daily OCTs. Surgery consisted of 23-gauge phacovitrectomy with internal...

Timing of vitrectomy for retained lens fragments

The purpose of this study was to compare the results of same setting vitrectomy with delayed vitrectomy for retained lens fragments following cataract surgery. Same setting vitrectomy was defined as the patient not leaving the operating table following cataract surgery....