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Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Intravitreal injections delivered by ophthalmic clinical nurse specialists

Intravitreal injections of the anti-vascular endothelial growth factor (anti-VEGF) agent ranibizumab, for the treatment of wet age-related macular degeneration (AMD) was approved by National Institute for Health & Care Excellence (NICE) in 2008 [1]. The Manchester Royal Eye Hospital (MREH),...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

Warfarin Induced Suprachoroidal Haemorrhage Presenting as Acute Angle Closure Glaucoma

Spontaneous suprachoroidal haemorrhage is a rare but recognised entity. Anticoagulant therapy is a well known risk factor. We describe a case of warfarin induced suprachoroidal haemorrhage presenting as acute angle closure glaucoma in a patient with raised International Normalised Ratio...

RNIB focusing on supporting patients to ‘wait well’ at point of diagnosis this National Eye Health Week

To coincide with National Eye Health Week (18-24 September), the Royal National Institute of Blind People (RNIB) has launched a free guide bringing together information about services, tips for questions to ask when attending hospital appointments, and links to emotional support to help while you wait to find out more.

Blind Football Fan ‘Scores’ Support

A Ross County supporter has praised the club and leading sight loss charity, RNIB Scotland, for helping him to keep attending games.

In conversation with Vasuki Sivagnanavel at 100% Optical

At 100% Optical at the end of February, we were lucky enough to run into Vasuki Sivagnanavel, Consultant Ophthalmic Surgeon at The Royal Eye Unit, Kingston Hospital, shortly after her presentation: 'Diagnostic insights with retinal ultra-widefield multimodal imaging - perspectives from an optometrist and ophthalmologist'.

The evolution and visual prognosis of glial proliferation of different grades after macular hole surgery

This retrospective research study aimed to investigate the evolution of glial proliferation of varying grades after successful idiopathic macular hole repair and its effects on foveal microstructure and best-corrected visual acuity (BCVA). Two-hundred and two eyes were enrolled in this...

Money never sleeps

“I want you to deal with your problems by becoming rich” As declared by Jordan Belfort in a motivational speech to his staff in the film Wolf of Wall Street (2013). Unfortunately, medicine as a career does not lead to...

Imaging papilloedema vs. pseudo-papilloedema

Quite often, in the working week as an ophthalmic photographer, you will be given that patient with ‘swollen discs’ to image. These swollen discs could be a number of things, but mainly fall into one of two categories: papilloedema or...

The implementation of postoperative day 1 vitrectomy telephone follow-up consultations

In this pre-COVID-19 study, the authors argue that some follow-up consultations can be done by telephone without compromising patient safety. Thirty years ago, a study by Isernhagen et al. [1] found that 52% of patients required some form of unexpected...

Recurrent corneal erosions secondary to isotretinoin use

Isotretinoin (13–cis-retinoic acid) is the first line treatment for moderate to severe nodulocystic or papulopustular acne [1,2]. Although it is a safe medication, it has several adverse side-effects, including ophthalmic manifestations, as shown in Table 1 [3]. These side-effects need...