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Rare eye diseases: progress continues with authorised orphan medicines and breakthrough technologies

1 October 2018 | | Ophthalmology
An update on the development of orphan medicines, recent regulatory treatment approvals for rare eye conditions and advances in retinal prosthetic technologies for blinding diseases. The prevalence of a rare disease is based usually on a range of estimates and...

Eye research: where next?

1 December 2017 | | Cornea / External Eye Disease, Cataract and Refractive, Glaucoma, Genetics, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
Eye research in the UK is underfunded relative to other areas of medical research and general awareness of sight loss and its prevention remains poor, messages that were reinforced in presentations and discussions during a recent research summit meeting in...

Optic nerve swelling – your survival guide (part 1)

1 August 2017 | | Neuro-Ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...

Emerging developments in dry eye

1 August 2017 | | Cornea / External Eye Disease
An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

An update on inherited retinal disorders (part 1) – overview and assessment of inherited retinal disease

1 October 2016 | | Retina / Uvea / Vitreous
Part 2 of this topic can be found here Inherited Retinal Disease (IRD) is the leading cause of blindness certification in the working age population (age 16-64 years) in England and Wales and the second most common in childhood [1]....

Pathophysiology of diabetic macular oedema: why combination therapy may be better

1 October 2015 | | Retina / Uvea / Vitreous
The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

1 October 2014 | | Cornea / External Eye Disease
“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Orbis marks 100-millionth antibiotic dose in the fight against trachoma in Ethiopia

12 May 2023 | Orbis, antibiotics, trachoma, Ethiopia
Orbis and partners mark historic 100-millionth dose of azithromycin antibiotics in the fight to eliminate blinding trachoma in Ethiopia by 2030. This milestone was achieved 20 years after Orbis began leading mass drug administrations.

Cataract care at Staffordshire eye hospital rated ‘outstanding’ by Care Quality Commission

29 May 2023 | spamedica, Cataract surgery, infrastructure
SpaMedica in Newcastle-under-Lyme has been awarded the highest possible rating following a recent inspection by the Care Quality Commission (CQC), the independent regulator of health and social care in England.

RNIB and British Blind Sport join forces to tackle the disparity of physical activity amongst blind and partially sighted people

31 May 2023 | RNIB, British Blind Sport, See Sport Differently, exercise, charity
The UK’s leading sight loss charity, Royal National Institute of Blind People (RNIB) and British Blind Sport have joined forces to launch the See Sport Differently campaign, which aims to promote accessible sports and breakdown barriers faced by blind and partially sighted people who want to get active.

Hot debates in medical retina and imaging: Perspectives from the Controversies in Ophthalmology 2020 virtual conference

5 August 2020 | | Ophthalmology, Retina / Uvea / Vitreous, Imaging
Controversies in medical retina and imaging were debated during the Controversies in Ophthalmology 2020 virtual conference held during two mid-day scientific sessions on 27 and 28 March 2020. The author recounts key perspectives and presents viewpoint recommendations from the Vision...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...