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Case Reports in Ophthalmology cover image

Conservative surgical management of optic disc pit maculopathy

5 August 2020 | | EYE - Vitreo-Retinal
Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...
Ophthalmic Genetics cover picture

Germline testing for uveal melanoma

4 December 2023 | | EYE - Pathology, EYE - Oncology | BAP1, Uveal melanoma, genetic counselling, hereditary cancer, mainstreaming, service delivery
The authors present a study of 114 consecutive patients presenting with uveal melanoma. Between 1 December 2019 and 1 November 2021 all patients over 18-years-old presenting to their centre with uveal melanoma were offered germline testing for variants in BAP1,...

Retinoblastoma management update (part 2): treatment, screening and surveillance, long-term follow-up and new developments

1 February 2017 | | EYE - Oncology
Retinoblastoma treatment requires significant multidisciplinary input, but early detection through raising awareness remains key to improving outcomes. In the second article of a two-part series, Manoj Parulekar discusses retinoblastoma management, screening and research. This article has been published in two...

A refractive surprise after vitrectomy and capsulectomy

1 February 2016 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oncology, EYE - Oculoplastic, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Figure 1: Right posterior capsule small aperture. We report a case of a pseudophakic patient who underwent vitrectomy and posterior capsulectomy. In spite of good visual acuity and absence of floaters, he was unhappy with the visual outcome. Case report...

Pegcetacoplan: A breakthrough treatment for dry age-related macular degeneration?

12 February 2025 | | EYE - Pathology, EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is a degenerative condition affecting the macula, the part of the retina responsible for central vision. It is characterised by the presence of drusen and retinal pigment epithelium (RPE) abnormalities in the absence of other macular...

Acute uveitis from late migration of soft lens matter 10 years post cataract surgery

3 June 2021 | | EYE - Cataract, EYE - Refractive, EYE - Imaging, EYE - General
A 58-year-old Caucasian male presented to the emergency eye clinic with a two-day history of a painful, red left eye and blurred vision. His past ocular history included uncomplicated left phacoemulsification cataract surgery in 2010 and left retinal detachment repair...

Shifting the paradigm of managing patients in medical retina: how real-world data can help us to improve clinical practice

1 February 2015 | | EYE - Vitreo-Retinal
The ophthalmic subspecialty of ‘medical retina’ has undergone dramatic changes in recent years. With the introduction of ranibizumab (Lucentis, Novartis), a specialty formerly dominated by laser-based therapies has been transformed to become, in large part, pharmacotherapy-based. To date, these pharmacotherapies...

Gene Vision launched to support those diagnosed with genetic eye diseases

2 December 2020
A new website, Gene Vision (https://gene.vision), has been developed by Professor Mariya Moosajee and Dr Alex Yeong, supported by Dr Peter Thomas (Director of Digital Innovation at Moorfields Eye Hospital). The new site is intended for adults, children and their families who are diagnosed with rare genetic eye diseases.

Did you need a mulligan, laddie?!

4 August 2025 |
Scotland is the home of golf. Golfing parlance infiltrates all walks of life here, including eye hospitals. It seems that my personal opinion on my compatriot Rory McIlroy’s completion of the golfing career grand slam is much more important to...

Conference Report: UCL Institute of Ophthalmology Summer School 2025

1 October 2025 | | conference report, meeting, event, training, education
The UCL Institute of Ophthalmology Summer School 2025 was held in collaboration with Moorfields Eye Hospital run by Gordon Hay and Tara Bader. This was a comprehensive five-day course attended by medical students and resident doctors from around the world....

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | EYE - Paediatrics, EYE - Neuro-ophthalmology, EYE - Orbit, EYE - General
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...

Flashes and floaters in community optometry – diagnosing a posterior vitreous detachment

1 October 2018 | | EYE - General
Managing patients who attend a practice with symptoms of flashes and floaters is a regular occurrence in community optometric practice. It’s often very distressing for patients; symptoms can be quite dramatic and an internet search can indicate imminent blindness from...