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Low dose steroids for ocular dry eye disease in graft vs. host disease

This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...

Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome

A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...

Ptosis procedure compared to upper blepharoplasty on dry eye syndrome

In this prospective, comparative case series, the authors compare the effect of combined blepharoplasty and Muller muscle conjunctival resection (MMCR) to an upper blepharoplasty in dry eye syndrome. The study was approved by the local institutional review board and participants...

Correlation between aqueous flare and macular microvascular status in diabetes mellitus

The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...

Associations with ocular surface disease in high school children

The authors aimed to determine the prevalence of ocular surface symptoms in a high school population and to evaluate its association with contact lens wear and other factors. The study had a population of 3240 students. This was a cross-sectional...

Relationship between diabetic retinopathy and cerebrovascular reactivity changes

Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...

Treatment of progressive keratoconus

This study aimed to analyse the clinical results of accelerated iontophoresis-assisted epithelium corneal cross-linking (i-ON CXL) to evaluate the risk factors for keratoconus progression after treatment, and the safety and efficacy of re-treatment using epithelium-off CXL protocol in paediatric patients....

TikTok video accuracy for paediatric ophthalmology videos

The purpose of this study was to systematically assess paediatric ophthalmology related TikTok videos based on author type, gender, content and engagement, and characterise the quality, medical accuracy, understandability and actionability of educational content. Search terms included adult strabismus, amblyopia,...

Amblyopia information provided by chatbots – how readable and understandable is this?

The purpose of this study was to evaluate the understandability, actionability and readability of responses to frequently asked questions about amblyopia provided by ChatGPT-3.5, Bing Chat, Bard and the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) website, along with...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Typical or surprisingly uncharacteristic presentations of neuro-ophthalmic emergencies

Irrespective of geographical location or patient cohort, emergency departments are high risk locations capable of inspiring extreme anxiety and dread in patients and doctors alike. The stress multiplies when a walk-in or referred case is suspected of underlying neurological pathology....

FOUNDATIONS OF INTRAOCULAR MICROSURGERY – Principles for Elite Performance Volume 1: Systemic Challenges

Cataract surgery is the most commonly performed intraocular surgery performed in the UK. It takes years of meticulous practice and experience to master the surgery and become a safe and slick surgeon. As the saying goes, “forewarned is forearmed.” Anticipating...