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Comparison of two interferon gamma release assays (IGRA) for tuberculous uveitis

In this prospective cohort study the authors compared QuantiFERON-TB Gold In-Tube and T-SPOT.TB to evaluate their diagnostic accuracy. They enrolled 120 consecutive new uveitis presentations over a two year period in a tertiary centre. The majority were Chinese (61.3%), followed...

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

In vivo confocal microscopy, principles and use in keratitis Part 1: Principles

In 1968 Maurice introduced the concept of high powered specular microscopy, it was in that very year that the first scanning confocal microscope was proposed. Marvin Minsky developed the first confocal microscope in 1955 named the ‘double focusing scanning microscope’....

Don’t ignore the black lesion! It might be mucormycosis

Keeping mucormycosis infection in the foreground of your differential diagnosis, especially in those more vulnerable patients, will help save their lives if recognised and managed appropriately. Mucormycosis is a fulminant infection caused by the fungi of the family Mucoraceae. It...

Results after 1.4mm biaxial cataract surgery and implantation of a new aspheric intraocular lens

The aim of this study was to analyse the clinical outcome and higher-order aberrations (HOAs) after 1.4mm biaxial micro incision cataract surgery (B-MICS) and implantation of a new aspheric intraocular lens (IOL). A total of 157 eyes of 106 patients...

A step-by-step approach to the diagnosis and management of Sands of Sahara Syndrome

Sands of Sahara syndrome (diffuse lamellar keratitis) is a rare postoperative complication of Laser in situ keratomileusis (LASIK). Its estimated prevalence is reported to be 2-4% among LASIK cases [1], despite that, it is more likely to be encountered by...

Customised corneal crosslinking with supplemental oxygen

In this prospective interventional case series, the authors investigate using supplemental oxygen delivery during epithelium-on corneal crosslinking (CXL) with specially designed oxygen delivery goggles. Twenty-seven eyes of 24 patients underwent epi-on CXL with Riboflavin and Ultraviolet-A irradiation. At six months...

In conversation with Andrena McElvanney (President, MCLOSA)

We spoke to Andrena about MCLOSA's annual meeting this November, key developments in cornea and external eye disease, and plans for the association’s 30th anniversary. Andrena McElvanney (top, second from right) and the OSI council members. The Medical Contact Lens...

My work experience with Great Ormond Street Hospital Young Persons’ Advisory Group for Research

For my school work experience I had the amazing opportunity to attend and work with the Great Ormond Street Hospital (GOSH) Young Persons’ Advisory Group for research (YPAG) (Figure 1). The GOSH YPAG is a group of young people aged...

Building research capacity through the VISION 2020 LINKS Programme

The aim is to build capacity for research in the region covered by the College of Ophthalmology of Eastern, Central and Southern Africa (COECSA). The project will build research capacity in three ophthalmology training institutions by ‘training the trainers’ and...

Intraocular Lens Surgery

This book is a valuable update on understanding IOL surgery for ophthalmologists in training and in practice. Broadly, the book is divided into six sections dealing with three main concepts: 1) IOL selection for routine and complex scenarios; 2) IOL...

‘Step Up For Nystagmus’ this Nystagmus Awareness Day

Monday 20 June, the Nystagmus Network marks Nystagmus Awareness Day by asking supporters to ‘Step Up For Nystagmus’ to raise awareness of this complex visual impairment.