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CD40L activation of human RPE cells
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
Progression of macular atrophy on long-term anti-VEGF therapy for AMD
This retrospective study evaluated the progression of macular atrophy in 53 eyes of 53 patients receiving AntiVEGF Therapy for age-related macular degeneration (nAMD), for at least six years. None of the patients had any macular atrophy (MA) at presentation. MA...The original smooth operator: Sir Robin Millar
As an early 80s kid, if you lacked sufficient pocket money, building a music collection entailed recording your favourite songs off the radio with a cassette deck and hoping the presenter didn’t interrupt at any point, with a finger hovering...A guide to the Multi-Speciality Recruitment Assessment (MSRA) exam
The MSRA exam is a mandatory part of the application for ophthalmology specialist training in the UK. It is a computer-based exam which is designed to assess junior doctors with foundation level competence. It is used for entry to postgraduate...Orbis marks 100-millionth antibiotic dose in the fight against trachoma in Ethiopia
Orbis and partners mark historic 100-millionth dose of azithromycin antibiotics in the fight to eliminate blinding trachoma in Ethiopia by 2030. This milestone was achieved 20 years after Orbis began leading mass drug administrations.Thyroid eye disease
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....
Inferior oblique adherence syndrome
A case is reported of a 14-year-old with inferior oblique muscle adherence and fat adherence following unilateral inferior oblique (IO) anteriorisation. Following surgery, the patient developed consecutive esotropia, ptosis and marked limitation of laevoelevation. Forced duction test was positive for...
Effects of orbital decompression
This is a retrospective review of 319 orbital decompression operations in 169 patients (73% female) with thyroid eye disease. Three wall decompressions were performed in 92 eyes, 2-wall in 206 (medial and floor), and a single wall (medial) in 18,...Blurred vision post liver transplant: to blame the house cat or not?
This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...Eyes on Tomorrow podcast: “Desert Island Discs for ophthalmologists”
What happens when an ophthalmologist and optometrist get chatting in a pub, over a couple of pints of Guinness, about how they could create something educational and entertaining for ophthalmologists and optometrists? The answer is the Eyes on Tomorrow podcast....SOS (Simplified Ophthalmic Statistics) Part 2: How to summarise your data and why it’s a good idea to do so
Studies involve capturing data. Statistical techniques allow data to be used to answer important research questions. A case series may have data on a handful of subjects but we are now entering the Big Data arena where datasets can be...
