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Hope for young children with impaired eye sight caused by Albinism

26 August 2025 | research, paediatric, new therapies, pharmacology
The University of Southampton has been awarded over half a million pounds for groundbreaking research aimed at improving the vision of children born with Albinism. Albinism affects the production of melanin – pigment which colours eyes, skin and hair. It...
Ophthalmology book cover

Ophthalmology

1 June 2019 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
The textbook is a large, single volume that ideally needs to be desk or table-supported, as its sheer weight makes it virtually impossible to rest comfortably on ones lap. The book is compiled by its two lead authors and editors...

Pituitary adenoma causing compression of the optic chiasm

1 April 2019 | | EYE - Neuro-ophthalmology, EYE - General
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...

Inherited retinal disorders now the leading cause of blindness

1 April 2014 | | EYE - Vitreo-Retinal
The recent paper in BMJ Open, from the UCL Institute of Ophthalmology, ‘A comparison of the causes of blindness certifications in England and Wales in working age adults (16-64 years), 1999-2000 with 2009-2010’ concludes that inherited retinal disorders (IRD) such...

Artificial intelligence and oculomics: Improving global health

2 June 2025 | | EYE - Imaging
The application of artificial intelligence (AI), and in particular deep learning, to high-resolution ocular imaging has led to many new discoveries, enabling the prediction of multiple different systemic diseases from ocular biomarkers. This emerging field is known as ‘oculomics’ [1]....

Transforming eyecare with AI at 100% Optical

4 March 2024 | Pearse Keane, AI, Moorfields, UCL, technology, advancement, artificial intelligence, development
“We are drowning in people we need to see in hospital eye services, and some people are going blind as a result. We are looking at nearly 10m hospital appointments for ophthalmology a year, with an approximately 33% increase over...

Haag-Streit launches Eyesi Indirect Ophthalmoscope ROP simulator for retinal examinations on preterm infants

5 April 2024 | Research & Development
The Eyesi Indirect ROP is a mixed-reality simulator that offers a highly immersive training environment for proper device handling, with an embedded, didactically structured simulator curriculum to teach the diagnostic skills required for correct ROP classification.

Macular imagery: observing the visual sensations pre- and post-Jetrea injections

25 September 2021 | | EYE - Vitreo-Retinal, EYE - General
A 63-year-old woman, a professional painter, was diagnosed with vitreomacular traction (VMT) in 2017. She had a history of metamorphopsia, drop in visual acuity (VA) in the left eye (6/6 in the RE; 6/18 in the LE), foveal vitreomacular traction...

Effect of minor trauma in eyes with previously undiagnosed angioid streaks

1 April 2014 | | EYE - Cataract, EYE - Cornea, EYE - General, EYE - Glaucoma, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - Oculoplastic, EYE - Oncology, EYE - Orbit, EYE - Paediatrics, EYE - Pathology, EYE - Refractive, EYE - Strabismus, EYE - Vitreo-Retinal
Angioid streaks (AS) may be associated with pseudoxanthoma elasticum (PXE), Paget’s disease, haemoglobulinopathies, Ehlers-Danlos Syndrome or abetalipoproteinaemia. Histopathology showed retinal pigment epithelium (RPE) and choriocapillaris loss, elastic fibre degeneration, calcium deposition, active choroidal neovascular membrane (CNVM) and vascular endothelial growth...

In conversation with Robert Henderson

14 November 2024 | EYE - Imaging, EYE - Paediatrics, EYE - Vitreo-Retinal
Revolutionary eye treatments offer hope for children facing blindness from CLN2 batten disease. Robert Henderson discusses this, and his use of Heidelberg Engineering’s Spectralis device to better combat it. Pioneering research from Great Ormond Street Hospital (GOSH) and the University...

Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Ocular electrophysiology

1 April 2014 | | EYE - Oculoplastic, EYE - Orbit
A 34-year-old woman, who is a CEO in a multinational firm, has been losing vision over the last 12 months. She has seen her opticians, who initially tried different glasses but could not improve things. Clinical examination is unremarkable. How...