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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...A new observation point: updating the nomenclature and classification with OCT
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...Sustainability in eyecare: Climate action in eyecare
Climate change will cause disruption to critical eyecare services and increases in rates of eye disease around the world. The International Agency for Prevention of Blindness has recommended 10 key areas of action on how the eyecare sector can address...Learnings and trends in the management of open-angle and angle-closure glaucoma
To be truly disruptive, newer technologies need to offer a quality of life benefit over medication to a broad population of glaucoma sufferers. Evidence and converging trends in medical and surgical management of glaucoma were explored in counterpoint discussions and...Pituitary tumours: why are they so often missed?
Part 2: Clinical varieties, anatomical considerations and case report (see also Part 1 and Part 3) For ophthalmologists there are four types of pituitary tumour to be considered, three of which are named according to the hormone secreted, along with...The challenges of rural optometry and how independent prescribing has helped
Why move from a busy professional independent Aberdeen optometry practice over 200 miles to one of the most remote places in the United Kingdom? I could talk about the professional challenge of supporting a rural community, or the chance to...The results of the last survey Oct22
I thank everyone for their time in responding to this edition’s survey questions. The first question relates to an issue I have previously discussed around consent for second eye cataract surgery. I touch on this point again for two reasons....Diabetic retinopathy screening in Belize: a country’s journey towards reducing blindness from DR
The rise of diabetes mellitus (DM) and its complications is a public health concern in the Caribbean. The Caribbean Diabetic Retinopathy (DR) Programme, managed by the London School of Hygiene & Tropical Medicine (LSHTM) and funded by the Queen Elizabeth...
