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The power of the full blood count

1 October 2021 | | Ophthalmology, Retina / Uvea / Vitreous
Vishal Shah walks us through his thought process whilst highlighting the importance of routine investigations when dealing with unusual retinovascular presentations. Retinal changes can arise in anaemia, leukaemia, lymphoma, myeloproliferative and myelodysplastic syndrome. They are often the first manifestation of...

Long-term effect of gene therapy on Leber’s congenital amaurosis

1 October 2015 | | Retina / Uvea / Vitreous
After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD

1 April 2017 | | Genetics
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | Ophthalmology, Paediatric Ophthalmology / Strabismus, Neuro-Ophthalmology, Orbit
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...

Space age surgery

1 October 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Oculoplastics, Ophthalmology, Optometry, Orbit, Ocular Pathology and Oncology, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
I asked to do theatre lists at Moorfields as part of my timetable. The medical retina fellow jobs are a bit odd in that the vast majority of the different rotations lack a regular theatre session. This might suit some...

Life in the eye department

1 June 2014 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
The crowd is gathering at the watering hole in the Serengeti that is Friday teaching at the Major Teaching Hospital. Would there be enough different species of consultant present or would there be insufficient numbers? If a critical mass of...

Surgical treatment of high myopia

1 June 2016 | | Cataract and Refractive
Although several excellent modalities are available for correcting high myopia, the surgical treatment of this condition remains one of the biggest challenges for refractive surgeons; this group of patients is often very dependent on contact lenses. If these patients become...

Initiatives in macular service provision

1 December 2015 | | Retina / Uvea / Vitreous
A report from Monitor in October 2015 identifies good practices that will realise most of the potential productivity gain in elective care available to NHS hospitals. These include: stratifying patients by risk and creating low-complexity pathways for lower-risk patients (tailoring...

A missed intraocular telescope – an opportunity to re-focus the evidence

4 February 2021 | | Ophthalmology, Cornea / External Eye Disease, Retina / Uvea / Vitreous, Imaging
Intraocular telescopes allow magnification of the image so that it would be projected into a larger area of the macula, this makes the central defect caused by dry age-related macular degeneration (AMD) smaller. The most common approach is a Galilean...

Blame the lens – not its position – in refractive surprise

3 February 2023 | | Ophthalmology, Cataract and Refractive
Aetiology of postoperative refractive surprise Weber coined the term “wrong eye, wrong intraocular lens, wrong patient” in 2008 as an aide memoir of major factors believed to underlie refractive surprise – defined as a significant unintended difference between dioptric refraction...

Traumatic optic neuropathy

1 October 2021 | | Ophthalmology, Orbit, Emergency Ophthalmology, Neuro-Ophthalmology
In neuro-ophthalmology we get asked a lot about management of patients who suffered significant trauma and presented with loss of vision secondary to presumed traumatic optic neuropathy (TON). TON happens usually in the context of significant craniofacial trauma. The incidence...

The past and the future for paediatric ophthalmology

1 June 2018 | | Paediatric Ophthalmology / Strabismus
The past 25 years have seen remarkable advances in clinical eye care for children in the UK. This has led to both improved outcomes and better patient and family experiences. There have been substantial changes to patient pathways, major advances...