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ANGPTL-4 inhibition reduces inflammation in diabetic retinopathy
Diabetic retinopathy (DR) is the most common cause of blindness in working-age humans, and numbers are rising due to increased cases of type 2 diabetes (T2D). T2D is associated with increased obesity and dyslipidaemia, which is a major risk factor...
Nicotine accelerates diabetes induced retinal changes
This study investigated the influence of nicotine in an experimentally induced diabetic rat model. They used non-invasive high-resolution spectral domain optical coherence tomography (SD-OCT) imaging to provide quantitative information on the temporal alterations of retinal structures at the micrometer resolution...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
Short-term effects of intravitreal bevacizumab on the cornea
Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...
Contrast sensitivity comparisons for Pelli Robson, Hiding Heidi and Double Happy tests
The authors aimed to compare contrast thresholds and measure agreement across current paediatric assessment of contrast sensitivity with Hiding Heidi and Double Happy contrast sensitivity tests vs. the gold-standard Pelli Robson chart. Reduced contrast levels were similar under different light...CALL TO ACTION: Help the Ridley Eye Foundation ‘reach more of the unreachable’ in the Himalayas
On the 29 November 1949, Harold Ridley carried out the first implant of an intraocular lens (IoL). This was the first major breakthrough in the cure of cataract blindness since Jacques Daviel conducted the first extra-capsular extraction 198 years earlier....The Global Vision Database
The overall goal of the Global Vision Database (GVD) [1] is to develop and deploy new and improved evidence on the prevalence of blindness and vision impairment (VI) globally. It is a repository which allows us to assess the causes...The perfect interview to land the dream consultant job
Eight top tips for consultant interviews: 1. A person is not just an ophthalmologist. Trusts are appointing the person not just the ophthalmologist. On a consultant interview panel (AAC) there will be non-ophthalmologists (e.g. medical director, chief executive, lay chair)...Impact of Eye Health Surveys and Partnerships in The Gambia
This article brings together the three national eye health surveys that have been undertaken in The Gambia between 1986 and 2019 and the impact that the results have had nationally and internationally. In it we describe the long-term capacity-strengthening for...
