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Contemporary glaucoma therapy: spoilt for choice
The goal of glaucoma management is to prevent visual loss and disease progression in the patient’s lifetime through effective lowering of intraocular pressure (IOP), the primary modifiable risk factor in glaucoma. Sustained and consistent IOP reduction is key to halting...In conversation with Vasuki Sivagnanavel at 100% Optical
At 100% Optical at the end of February, we were lucky enough to run into Vasuki Sivagnanavel, Consultant Ophthalmic Surgeon at The Royal Eye Unit, Kingston Hospital, shortly after her presentation: 'Diagnostic insights with retinal ultra-widefield multimodal imaging - perspectives from an optometrist and ophthalmologist'.
The evolution and visual prognosis of glial proliferation of different grades after macular hole surgery
This retrospective research study aimed to investigate the evolution of glial proliferation of varying grades after successful idiopathic macular hole repair and its effects on foveal microstructure and best-corrected visual acuity (BCVA). Two-hundred and two eyes were enrolled in this...Congratulations to the SOC poster prize winners!
The Scottish Ophthalmological Club (SOC) recently hosted another excellent webinar on the theme ‘Post COVID – The Best of Times and The Worst of Times'.
Progression of retinitis pigmentosa
This retrospective study evaluates the rate of progression of retinitis pigmentosa (RP) using multimodal imaging, including spectral-domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF) and microperimtery (MP). Traditional tests used to evaluate RP, for example, Goldmann visual fields and ERG...
Hypothyroidsim and acute central serous chorioretinopathy – is there a link?
This cross-sectional study included 71 consecutive acute central serous chorioretinopathy (CSC) patients and 70 age-matched healthy control subjects. Systemic findings, including serum levels of thyroid hormones, thyroid stimulating hormone (TSH), mean arterial pressure (MAP), pulse rate, serum lipid levels and...
Anatomical and functional outcomes following switching from aflibercept to ranibizumab in NARMD
This is a six-month, prospective, single-arm study in the UK and Germany. A total of 100 patients were enrolled (one in the primary failure group, 99 in the suboptimal treatment response group), treated three-monthly intravitreal ranibizumab injections (0.5mg), and then...
Silicone oil migration presenting as an eyelid cyst
The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...
Conservative surgical management of optic disc pit maculopathy
Four cases are presented in this case report that illustrates the option of conservative surgical management for optic disc pit complicated by maculopathy (ODP-M). Four men aged 24-67-years-old with no spontaneous resolution of ODP-M for a minimum of three months,...
Intravitreal Ziv-Aflibercept: safety analysis
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...
Characteristics of limbal lymphatic vasculature on confocal microscopy
This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...
