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1957 results found

Macular atrophy and choriocapillaris nonperfusion

This Japanese study compared the choriocapillaris (CC) nonperfusion area as measured on OCTA with areas of macular atrophy (MA) measured by fundus autofluoresence (FAF). A total of 44 eyes were assessed (31 were treated with anti-VEGF alone and 13 had...

OCTA FAZ measurements in vein occlusion

Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...

Retinal changes in Leber hereditary optic neuropathy

The objective of this study was to describe the changes in the retinal ganglion cell complex (GCC) relative to the retinal nerve fibre layer (RNFL) over time, in patients with Leber’s hereditary optic neuropathy (LHON). For this study, 21 patients...

OCT use with macular retinoblastoma

The authors explore the use of portable hand-held spectral domain OCT (SD-OCT) in three eyes of three infants and young children with macular retinoblastoma. All were treated with chemotherapy and all had SD-OCT before and after treatment. The children were...

The prevalence of macular cysts in patients with clinical cone-rod dystrophy determined by spectral domain optical coherence tomography

Cone-rod dystrophy is a progressive photoreceptor disorder which has multiple inheritance patterns. It is rare, with a prevalence of 1 in 40,000. Macular cysts are well recognised in other photoreceptor conditions such as retinitis pigments and choroideraemia, while they are...

Swept source anterior segment OCT

The authors describe a study using the Casia OCT which is a swept source OCT to determine the visibility of the angle structures using two imaging protocols; high density and low density. They randomly selected one eye from 30 normal...

Binocular single vision (BSV)

Introduction In this article I will try to summarise some of the definitions, tests and assessments performed in the strabismus clinic to assess patient binocular potential. This is a key feature of strabismus assessment, especially in adults, and it will...

Medial rectus anatomy in exotropia

This study investigates the differences between extraocular muscles in patients with intermittent exotropia and normal controls regarding muscle fibre arrangement and diameter, and distribution and activation of satellite cells. Fifteen patients were recruited having medial rectus resection surgery. Resection sections...

Germline testing for uveal melanoma

The authors present a study of 114 consecutive patients presenting with uveal melanoma. Between 1 December 2019 and 1 November 2021 all patients over 18-years-old presenting to their centre with uveal melanoma were offered germline testing for variants in BAP1,...

Preoperative RPE alterations in macular holes

This retrospective interventional case series from Japan assessed whether preoperative alterations of the retinal pigment epithelial (RPE) in idiopathic macular holes correlated with postoperative functional and morphological changes in the macula. Fifty-nine eyes had preoperative Spectralis OCT using the ‘detailed’...

Sex differences in the relationship between obesity and choroidal nevus in US adults

The National Health and Nutrition Examination Survey (NHANES); a population-based survey conducted annually in the US by the Centers for Disease Control and Prevention, was used to identify populations at higher risk for choroidal naevus. Over a period of four...

Macular atrophy with aflibercept

The authors of this paper set out to investigate the prevalence of macular atrophy in treatment-naive patients with neovascular AMD undergoing aflibercept monotherapy (three monthly loading injections followed by subsequent treatment every two months). Case notes over a three year...