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Ophthalmology journal front cover image.

Low-dose bimatoprost/timolol gel: a new fixed-combination option

3 February 2026 | | EYE - Glaucoma
This phase III international randomised trial evaluated the efficacy and safety of a new low concentration bimatoprost/timolol eye gel (bimatoprost 0.01%/timolol 0.1%). It was compared with the conventional higher-strength fixed combination eye drops (bimatoprost 0.03%/timolol 0.5%) in patients with open-angle...

5-FU vs. Avastin as adjunct to conjunctival autograft

1 October 2016 | | EYE - Cornea, EYE - General
The authors compare the outcome of pterygium treatment using 5-fluorouracil as an adjunct to free conjunctival autograft versus bevacizumab (Avastin) as an adjunct to free conjunctival autograft, via a randomised controlled prospective study. Seventy eyes of 70 patients were included...

Culture positivity of needles for IVT injections

1 December 2013 | | EYE - Vitreo-Retinal
Given the worldwide use of intravitreal (IVT) injections, the authors of this paper set out to evaluate the rate of culture positivity of the needles used in routine IVT injections and compare this positivity between 27-gauge and 30-gauge needle tips....
Ophthalmologica journal cover image

Sickle cell maculopathy

1 October 2021 | | EYE - Vitreo-Retinal | OCT imaging, Sickle cell disease, Sickle cell maculopathy, Visual impairment
This paper reports the result of a prospective study to analyse the prevalence of sickle cell maculopathy (SCM) and its associations with age, sex, genotype, proliferative sickle cell retinopathy (PSR) stage, and the impact on visual acuity (VA). This study...

Ciliatech reports positive clinical results on novel glaucoma implant, CID, in 24-month post-operative follow up

29 March 2023 | glaucoma
Chavanod (near Annecy), France, March 29, 2023 - Ciliatech, an ophthalmology medtech company developing a new class of implant to treat glaucoma durably, announced the positive results of a 24-month post-operative follow-up on a clinical trial of CID, its first generation Cilio-scleral Inter-positioning Device.

Triamcinolone (TA) deposits following subcutaneous injection to treat chalazion

2 August 2022 | | EYE - Oculoplastic, EYE - General
Chalazia are chronic lipogranulomatous inflammations of the eyelid secondary to a blocked meibomian gland. Whilst most resolve spontaneously, certain chalazia warrant treatment. Options include incision and curettage (I&C), lesion excision, intralesional steroid injections, and botox injections [1]. I&C is usually...

In conversation with Robert MacLaren

2 December 2019 | EYE - Vitreo-Retinal, EYE - General
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Addressing medical risk factors for diabetes and understanding the new systemic treatments

1 February 2014 |
As global diabetes figures continue to rise, the importance of reducing the burden of macrovascular and microvascular complications of diabetes has never been so great. By 2025 it is estimated that five million people in the UK will have diabetes...

Oct/Nov 2019 Quiz

1 October 2019 | EYE - General
History A 62-year-old female patient was referred for rapid growth of a left periorbital soft tissue lesion with proptosis. Her past medical history included: hypertension, hyperlipidaemia and bipolar disorder. On examination: vision in the affected eye was hand movements, right...

Iris chafing from displaced single-piece acrylic IOL

4 August 2021 | | EYE - Cataract, EYE - Refractive, EYE - Imaging, EYE - General
A 74-year-old man had persistent 3+ cell one month following left eye cataract extraction, complicated by anterior capsular rent and zonular dialysis at 7 o’clock, with single-piece acrylic intraocular lens implantation (IOL) in the capsular bag. Figure 1: Haptic-like transillumination...

On the wrong track

1 June 2015 | | EYE - Cataract, EYE - Refractive, EYE - Imaging, EYE - Vitreo-Retinal, EYE - General
A 65-year-old very high myope lady presented with sudden blurred vision down to count fingers to her right eye after a short and sharp pain. She also described seeing a black swirly line and as all these symptoms were exactly...