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Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

The International Council of Ophthalmology: what is it and is it useful for UK ophthalmologists?

ICO Director for Examinations and Assessments, Simon Keightley, explains the history and role of the organisation today, as well as outlining recent changes to the ICO examinations. The International Council of Ophthalmology (ICO) is the only international medical specialty organisation...

Outcomes of cataract surgery in eyes with weak zonules

Pseudoexfoliation (PEX) and zonular weakness have long been known to increase the risk of complication of cataract surgery. This retrospective study looks at the results of phacoemulsion and intraocular implantation in 295 eyes with pseudoexfoliation and zonular weakness, with a...

Health-related quality of life after cataract surgery

This prospective study evaluates the impact of cataract surgery on subjects’ health-related quality of life (HRQoL) measured with a 15-dimension generic instrument, the 15D. The HRQoL of cataract subjects was compared with that of an age- and gender-standardised sample of...

Collamer lenses for accommodative ET

Posterior chamber phakic IOL implantation was used to treat patients with accommodative esotropia (ET) with the goal of eliminating hyperopia and producing orthophoria. Three patients (six eyes) aged 18-22 years had an average follow-up of 17 months ±6.24. The mean...

Visual field progression after glaucoma drainage device implantation

This retrospective interventional case series assessed changes to visual fields after implantation of a glaucoma drainage device (Baerveldt, Ahmed or Molteno Devices) between 2010 and 2015. A total of 106 eyes from 96 patients were included in the final analysis...

Secondary glaucoma post paediatric cataract surgery

This retrospective observational consecutive case series assessed the incidence and risk factors associated with developing glaucoma after paediatric cataract surgery with primary intraocular lens (IOL) implantation. They reviewed 136 children (199 eyes) who underwent paediatric cataract surgery before the age...

Clinical outcomes of a supplementary sulcus IOL

In this retrospective study, the authors examined 31 eyes of 20 patients who had received a supplementary trifocal sulcus IOL in addition to a ‘bag-in-the-lens’ IOL. Implantation of a ‘bag-in-the-lens’ IOL requires the creation of anterior and posterior capsulotomies, followed...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Screening for Sickle Cell Retinopathy (SCR): Why we do wide-field imaging, OCT/OCT-A for SCR – Newcastle upon Tyne Hospitals NHS Foundation Trust

I have been working in ophthalmology for over five years as a photographer and research co-ordinator, and it is fascinating, rewarding, and interesting to learn all about the different diseases associated with the eye. One condition that has been a...

How are pigment dispersion syndrome and pigmentary glaucoma inherited?

This single centre prospective, cross-sectional study assessed the relatives of patients with pigment dispersion syndrome (PDS) and pigmentary glaucoma (PG) to determine the heritability of these conditions over an 11 month period. One hundred and one unrelated patients with PDS...

Trans-sinus endoscopic removal of retrobulbar air gun pellet within the orbital apex

Injuries to the eye have been widely reported in medical literature due to a variety of mechanisms causing significant morbidity and occasional unexpected mortality for the patient [1]. It is often wrongly assumed that air gun pellets lack this potential....