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Medical management and diabetic retinopathy progression

1 February 2015 | | Retina / Uvea / Vitreous
The ACCORD Eye Study was designed to evaluate the benefit of intensive glycaemic control (HbA1c <6.0% vs 7.0-7.9%), intensive systolic blood pressure control (<120mmHg vs. <140mmHg), and combined fenofibrate and simvastatin therapy in the development and progression of diabetic retinopathy....

Long-term open angle glaucoma cohort study

1 December 2014 | | Glaucoma
This was a study to estimate the development of open angle glaucoma (OAG) in a screened and re-examined elderly group as compared to an unscreened group during the same time period. The participants comprised of 856 individuals born in 1915...

Nystagmus and associated diagnosis

1 December 2014 | | Paediatric Ophthalmology / Strabismus | achromatopsia, congenital nystagmus, foveal hypoplasia, nystagmus
Patients with nystagmus attending a Low Vision clinic in Sweden were included in this study. Medical records were reviewed to exclude those with general diagnoses that could explain the nystagmus. The remaining group of patients underwent subjective refraction, retinoscopy, ocular...

Risk factors for amblyopia

1 April 2014 | | Paediatric Ophthalmology / Strabismus
The author presents a meta-analysis of published data to estimate American Association for Pediatric Ophthalmology and Strabismus (AAPOS) prevalence data for amblyopia risk factors. He extracted data from major paediatric comprehensive eye examination studies for children aged two to five...

Short-term outcome after intravitreal ranibizumab injections for ROP

1 December 2013 | | Retina / Uvea / Vitreous | Child health (paediatrics), Retina
This is an interventional case series study of three premature babies (six eyes) with high risk prethreshold or threshold retinopathy of prematurity (ROP) with plus disease that received intravitreal ranibizumab injections for ROP. All infants received intravitreal ranibizumab injections of...

Macular oedema after cataract surgery in diabetic patients

1 December 2013 | | Retina / Uvea / Vitreous
The authors describe a multi-centre prospective observational study of 293 participants that underwent cataract surgery who all had diabetic retinopathy without definite central-involved macular oedema. Forty-five clinical sites took part throughout the United States. Patients were eligible if there was...

Case presentation: seizures as a presenting sign of idiopathic intracranial hypertension

3 June 2024 | | Neuro-Ophthalmology
Idiopathic intracranial hypertension (IIH) is a syndrome of isolated elevated intracranial pressure of unknown cause. Neurological examination in IIH is typically normal except for papilloedema and possible cranial nerve six palsy, although rare, atypical symptoms and signs can occur. With...

Avoiding investigations through history taking and examinations to differentiate serious from comparably benign aetiology

1 December 2022 | | Ophthalmology
*Joint first authors. Introduction Anisocoria can be a sign of neurological deficit, necessitating numerous investigations [1]. This case report explores how expensive and time-consuming investigations can be avoided by thorough history taking and examination to differentiate serious from comparably benign...

An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment

5 April 2022 | | Ophthalmology, Cornea / External Eye Disease
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...

Irido-corneal endothelial syndrome: an overview

24 January 2022 | | Ophthalmology, Optometry, Cornea / External Eye Disease, Glaucoma, Imaging, ONLINE EXCLUSIVE ARTICLES
Irido-corneal endothelial (ICE) syndrome is a rare group of eye related disorders that constitute three different clinical entities: Chandler syndrome (CS), essential / progressive iris atrophy and iris naevus / Cogan-Reese syndrome. ICE syndrome is sporadic in its presentation as...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

1 April 2019 | | Ophthalmology, Cornea / External Eye Disease
An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Ophthalmology in ancient india, Sushruta’s time and the modern era

1 August 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
While reading an article related to the history of Indian ophthalmology, I came across this description of a surgical procedure: “The doctor warmed the patient’s eye with the breath of his mouth. He rubbed the closed eye of the patient...