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921 results found

Twenty-four hour IOP patterns in patients with thyroid eye disease (OO/GL)

1 August 2015 | | Oculoplastics, Orbit | contact lens sensor, glaucoma, intraocular pressure, thyroid eye disease
Elevated IOP in patients with thyroid eye disease (TED) can be caused by restriction and compression of the globe by enlarged extraocular muscles, elevated episcleral venous pressure and increased mucopolysaccharide deposition in the trabecular meshwork. Although previous studies have investigated...

Intravitreal dexamethasone implant for diabetic macular oedema

1 February 2015 | | Paediatric Ophthalmology / Strabismus
The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Retinal blood flow changes in glaucoma

1 December 2014 | | Glaucoma | Heidelberg Retina Flowmeter, retinal blood flow, retinal vessel analyser, retinal vessel diameter
This study examined the changes in retinal blood flow and vessel diameter after IOP reduction in high- and low-pressure glaucoma; exfoliation glaucoma (ExG) and normal-tension glaucoma (NTG). Glaucoma progression is seen at times in eyes despite IOP reduction and changes...

The choroid in pregnancy

1 October 2014 | | Retina / Uvea / Vitreous
During pregnancy there can be different types of ocular changes including a decrease in corneal sensitivity, increase in central corneal thickness and curvature, decrease in intraocular pressure, central serous chorioretinopathy and ocular blood flow. Advances in ophthalmic imaging devices has...
Journal of Glaucoma front cover image.

Blood pressure association with primary open angle glaucoma severity

31 May 2024 | | Glaucoma
This prospective observational study involved 47 patients diagnosed with primary open angle glaucoma (POAG) examined to investigate their postural blood pressure response and its potential correlation with the severity of glaucomatous optic neuropathy (GON). Participants underwent intraocular pressure and systemic...

A revolution in modern genetic testing for the clinical management of ocular disease

1 August 2016 | | Cataract and Refractive, Cornea / External Eye Disease, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Ophthalmology, Oculoplastics, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous, AMD, Emergency Ophthalmology
Recent years have seen a huge increase in our understanding of the genetic factors underlying a wide variety of eye diseases. This has included common conditions such as glaucoma and age-related macular degeneration, as well as those conditions which have...

What's trending Dec/Jan 2021

7 December 2020 | | Ophthalmology, Optometry, Retina / Uvea / Vitreous, Cataract and Refractive
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #threeblindmice US company Nanoscope Therapeutics has developed a new treatment which is hoped will restore vision in those affected by retinal...

Diabetic Macular Oedema

1 December 2013 |
Diabetes mellitus is a metabolic disorder that affects the metabolism of all three categories of carbohydrates, lipids and proteins. This condition is characterised by chronic hyperglycaemia [1]. This can cause end organ damage. The estimated worldwide diabetes prevalence for 2010...

Retinoblastoma management update (part 1): clinical features, diagnosis and genetics

1 January 2017 | | Ocular Pathology and Oncology
The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 1)

3 February 2023 | | Ophthalmology
Part 1: Epidemiology, classification, radiology, histopathology and associations (see Part 2 here) In this two-part series, Li Yen Goh reviews IgG4 disease and reminds us of diagnostic challenges faced. Introduction Immunoglobulin G4 (IgG4) disease is a recently recognised idiopathic systemic...

The embryology of the eye

1 December 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Nobody claims to like embryology. At least nobody I know. It has been a neglected part of the curriculum since time immemorial and a vicious cycle occurs in which those with an incomplete understanding fail to appreciate the inherent beauty...

Optic nerve swelling – your survival guide (part 1)

1 August 2017 | | Neuro-Ophthalmology
Assessment of optic nerve appearance and functions is a daily routine in neuro-ophthalmology. Following a recent high profile court case there has been a significant increase in the amount of referral to ophthalmology departments to assess the optic nerve and...