You searched for " cornea"
Outcomes of corneal collagen crosslinking (CXL) in pseudophakic bullous keratopathy (PBK)
1 August 2014
| Sharmina Khan
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Cornea / External Eye Disease
This was a retrospective non-comparative, interventional case series of 50 eyes in 50 patients with symptomatic PBK who underwent CXL (epithelium-off). Central corneal thickness (CCT), pain score, best corrected visual acuity (BCVA), and corneal transparency were recorded at baseline; at...
Corneal lenticule allotransplant
1 April 2017
| Magdalena Popiela
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Cornea / External Eye Disease
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
Quarter DMEK
1 February 2017
| Magdalena Popiela
|
Cornea / External Eye Disease
This case report describes a novel technique where one quarter of Descemet’s membrane (DM) was transplanted during a quarter-descemet membrane endothelial keratoplasty (DMEK) procedure. DMEK graft was prepared from a 58-year-old corneo-scleral donor after one week in culture. Peripheral DM...
Inhibiting high-risk corneal allografts
1 October 2014
| Graham Wallace
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Cornea / External Eye Disease
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T regulatory cells, Tim-1, high-risk corneal allograft rejection, mice
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Descemetorhexis without endothelial keratoplasty
1 June 2018
| Magdalena Popiela
|
Cornea / External Eye Disease
This retrospective study examined outcomes of the largest reported series of eyes, which underwent Descemetorhexis without endothelial keratoplasty (DWEK) for Fuch’s endothelial dystrophy with mean 10 months of follow-up. Seventeen eyes were included in analysis; with 82.4% achieving corneal clearance...
Corneal suture sample evaluation
This is a prospective study of 35 patients’ suture samples taken from a tertiary cornea clinic, Miami, Florida, with a history of penetrating keratoplasty. The aim is to study the relationship between corneal suture bacteriology, biofilm and the clinical setting,...MicroRNA inhibits corneal neovascularisation
1 August 2018
| Graham Wallace
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Cornea / External Eye Disease
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Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
Platelet rich fibrin membrane for descemetocele
1 December 2016
| Magdalena Popiela
|
Cornea / External Eye Disease
This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...
BESTi: a new index to detect subclinical keratoconus
3 October 2022
| Mahmoud Ahmed
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Cornea / External Eye Disease
In this multicentre, case-control study, the authors develop a new index, named Boosted Ectasia Susceptibility Tomography Index (BESTi), to detect early cases of keratoconus. This index was derived from multiple logistic regression analysis of 22 variables of tomography scans. The...
Central corneal and epithelial thickness measured by Fourier domain OCT
1 April 2016
| Magdalena Popiela
|
Cornea / External Eye Disease
This study examined intraobserver and interobserver reproducibility of corneal thickness (CT) and epithelial thickness (ET) measurement of Fourier domain OCT (RTVue) in 23 healthy volunteers. RTVue is capable of producing 26,000 A scans per second with depth resolution of 5µm....
Differences of the anterior segment parameters in children with Down syndrome
1 August 2014
| Huw Edward Oliphant
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Cataract and Refractive
This cross-sectional study was designed in order to demonstrate the differences in anterior segment parameters in children with trisomy 21. This is important as it may impact on surgical planning when undertaking procedures in the anterior segment such as corneal...
Corneal thickness in patients with diabetic peripheral neuropathy
1 October 2018
| Bushra Thajudeen
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Cornea / External Eye Disease
This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...