You searched for "fluorescein"
Evaluation of fluocinolone acetonide in the management of BRC
1 June 2022
| Jonathan Chan
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Retina / Uvea / Vitreous
This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...
Lacquer cracks
1 August 2019
| Saruban Pasu
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Retina / Uvea / Vitreous
The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...
Radiation maculopathy
1 December 2018
| Jonathan Chan
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Retina / Uvea / Vitreous
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Inflammation, Macula, Pathology, Retina, Treatment Medical
This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...
Managing orbital compartment syndrome
1 April 2018
| Jaya Myneni
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Oculoplastics, Orbit
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Canthotomy, orbital compartment syndrome, orbital hemorrhage, orbital pressure, orbital trauma
This experimental study using cadaveric models was done to evaluate the surgical technique effective in relieving orbital compartment syndrome. Twelve cadaveric orbits were injected with blood analogue stained with fluorescein. Pressure probes were inserted in superotemporal (advanced 40mm into orbit)...
OCT changes in chronic optic neuropathy
1 October 2017
| Claire Howard
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Neuro-Ophthalmology
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OCT angiography, optic neuropathy, peripapillary capillaries
The authors evaluated optical coherence tomography (OCT) angiography in 10 patients who suffered various types of chronic optic neuropathies. Glaucoma is known to cause a decrease in peripapillary perfused capillary density on OCT angiography. However, other optic neuropathies have not...
Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?
1 August 2016
| Magdalena Popiela
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Cornea / External Eye Disease
This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...
Treatment of Sjogren’s Syndrome dry eye in mouse model
1 April 2016
| Graham Wallace
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Cornea / External Eye Disease
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Autoimmune, Chronic, Conjunctiva, Inflammation, Ocular surface, Sjögren's syndrome
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...
Meibomian gland dropout in patients with dry eyes
1 December 2014
| Khadijah Basheer
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Cornea / External Eye Disease
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Dry eye disease, meibomian gland, non-contact meibography system
In this prospective study 264 patients with symptoms of dry eye were examined with a non-contact meibography system to assess the morphological changes in their meibomian glands. These patients were not previously diagnosed with meibomian gland dysfunction and patients with...
Ocular ischaemic syndrome in a rat model
1 December 2014
| Claire Howard
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Neuro-Ophthalmology
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Animal model, controllable needle suture method, fluorescein fundus angiography, laser doppler flowmetry, retinal ischaemia
Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...
Vital dyes in ophthalmology
1 October 2014
| Khadijah Basheer
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Ocular Pathology and Oncology
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Chromovitrectomy, indocyanine green, staining, trypan blue, vital dye
This comprehensive review gives an excellent summary of the uses and properties of the different dyes available to aid better visualisation and diagnoses in ophthalmology. The authors clearly display the pharmacological properties, molecular details, osmolarity and indications in clinical ophthalmology...
Pterygium ocular surface temperature
1 August 2014
| Khadijah Basheer
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Cornea / External Eye Disease
This prospective study investigated the ocular surface temperature in patients with pterygia compared to those with dry and healthy eyes respectively. Previous studies have shown that patients with dry eyes show a significant decrease in ocular surface temperature on sustained...
Effects of topical anaesthetic on intraocular pressure
1 August 2014
| Nana Theodorou
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Glaucoma
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Goldmann applanation tonometry, applanation resonance tonometry, aqueous humor, intraocular pressure, repeated tonometry
This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...