You searched for "macular degeneration"
OCT measurements in neurodevelopmental conditions
The authors aimed to investigate what changes occur in the retinal nerve fibre layer (RNFL), ganglion cell layer (GCL) and macula when specific learning disorder (SLD) comorbidity is added to attention deficit hyperactivity disorder (ADHD). They compared measures in three...
Using OCT to screen and monitor Alzheimer’s disease
1 June 2016
| Claire Howard
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EYE - Neuro-ophthalmology
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Macular thickness, mild cognitive impairment, optical coherence tomography, subjective memory complaints
Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...
Detecting apoptosis in retinal cells
1 February 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...
Corneal thickness in patients with diabetic peripheral neuropathy
This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...Eye scans detect signs of Parkinson’s disease up to seven years before diagnosis
22 August 2023
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moorfields, Parkinson's disease, Siegfried Wagner, Pearse Keane, UCL Institute of Ophthalmology, early detection
A team led by Siegfried Wagner and Pearse Keane of Moorfields Eye Hospital and UCL Institute of Ophthalmology (and spanning UCL institutions) has identified markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation.
Strengthening the signal: Advancing oculomics research for systemic health insights
4 December 2024
| Mertcan Sevgi, Siegfried Wagner
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EYE - Imaging
Oculomics, the study of how ocular structure reflects systemic health, is poised to become an integral tool for predicting, triaging, and diagnosing a wide range of diseases. By analysing data from the eye, particularly the retina, healthcare providers can gain...
Oculomics and Big Data changes the game for Medical Ophthalmologists
25 September 2023
| Nima John Ghadiri
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oculomics, Nima Ghadiri, big data, ai, artificial intelligence, RETFound, Alastair Denniston
Oculomics and Big Data changes the game for Medical Ophthalmologists, and here's why.
In conversation with Robert MacLaren
2 December 2019
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EYE - Vitreo-Retinal, EYE - General
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...
Stem cell therapy for Parkinson’s disease: researching for an effective cure
1 December 2015
| Romina Vuono
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EYE - Neuro-ophthalmology
Neurodegenerative diseases are characterised by the chronic and progressive loss of neurons, which in turn results in loss of cognitive and physical functions. The World Health Organization has estimated that the disability-adjusted life years lost from neurological disease was about...
Oculogyric crisis with B12 deficiency
1 June 2022
| Jack Henderson, Colm McCarthy
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EYE - Neuro-ophthalmology, EYE - Imaging, EYE - General
An oculogyric crisis (OGC) is a dystonic movement disorder of the eyes which can last from seconds to hours. Although there is no published diagnostic criteria for OGC, typically the onset is acute, and it is characterised by conjugate upward...
AI & Oculomics: a new section for Eye News
2 February 2024
| Nima John Ghadiri
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EYE - General
Inaugurating this new regular section on the exciting landscape of AI and oculomics, we provide an overview which delves into the historical context and the etymology of this field, reviews the current state of play and contemplates possibilities and hopes...
Corporate M&A pace gathers momentum
1 October 2019
| Rod McNeil
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EYE - General
Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...
