You searched for "retina"
New grading description for ROP retinal changes for those meeting termination of vision screening guidelines
3 June 2024
| Fiona Rowe (Prof)
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Paediatric Ophthalmology / Strabismus
This study reports and characterises residual retinal changes seen in eyes that meet criteria for termination of acute retinal screening exams. A novel grading system was used in which retinal exams were graded A to E. ‘A’ was defined as...
Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma
The book is divided into three sections: an introduction to optical coherence tomography (OCT), the OCT in macular diseases, and glaucoma. The first section lists the currently commercially available OCT machines, then describes the techniques for acquiring OCT images using...Inflammation and microvascular changes in diabetic retinopathy
1 February 2022
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Aqueous flare, diabetes mellitus, diabetic retinal neuropathy, diabetic retinopathy, intraocular inflammation, neuroinflammation
Studies have shown that neurodegeneration and inflammation in the retina start early in diabetic retinopathy (DR) and can be present before the latter is clinically evident. The aim of this retrospective review of 99 diabetic patients was to evaluate retinal...
Can OCT predict Alzheimer’s disease?
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Can OCT predict Alzheimer’s disease? In 1986 Hinton et al. demonstrated evidence of optic nerve degeneration...Bionic eyes: deciphering the neural circuitry of vision restoration
3 June 2024
| Muhammad Khursheed Ullah Khan Marwat
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Ophthalmology
As the boundaries between technology and biology blur, retinal prosthetics, often dubbed ‘bionic eyes’, present a ground-breaking paradigm shift in addressing blindness. This article delves into the captivating scientific intricacies of these neural interfaces, exploring their mechanisms of action, current...
Histopathological changes in rabbit retinitis pigmentosa
1 April 2017
| Claire Howard
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Neuro-Ophthalmology
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Optic disc, optic nerve, rabbit, retinal ganglion cell, retinitis pigmentosa
The authors report the histopathological changes of retinal ganglion cells (RGCs), optic disc and optic nerve in rabbit with advanced retinitis pigmentosa (RP). RP was recreated in rabbits by using bacterial artificial chromosome transgenesis, with the purpose of increasing understanding...
Optos announces new ultra-widefield colour image modality, providing additional retinal visualisation to eyecare professionals
Optos, Plc, the leading retinal imaging company, announces it is expanding the optomap® ultra-widefield (UWF™) retinal imaging modalities available with the California FA device to further assist eyecare professionals in disease management and treatment planning.Retinal blood flow changes in glaucoma
1 December 2014
| Nana Theodorou
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Glaucoma
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Heidelberg Retina Flowmeter, retinal blood flow, retinal vessel analyser, retinal vessel diameter
This study examined the changes in retinal blood flow and vessel diameter after IOP reduction in high- and low-pressure glaucoma; exfoliation glaucoma (ExG) and normal-tension glaucoma (NTG). Glaucoma progression is seen at times in eyes despite IOP reduction and changes...
Age-related macular degeneration
1 December 2015
| Nana Theodorou
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Retina / Uvea / Vitreous
This review article offers an up to date review of the genetic and environmental risk factors associated with aetiology surrounding age-related macular degeneration (AMD). The article briefly describes the typical clinical presentation relating to early and late stages of the...
An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs
1 December 2016
| Stacey Strong, Michel Michaelides (Prof)
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Retina / Uvea / Vitreous
Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...
The challenge of chorioretinal folds in virtual eye clinics
3 June 2024
| Noorulain Khalid, Faizan Hashmi, Adam Riaz, Hadi Ziaei, Abha Gupta
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Retina / Uvea / Vitreous, Orbit
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...
Somatostatin protects retinal pericytes
1 April 2018
| Graham Wallace
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Retina / Uvea / Vitreous
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Apoptosis, Diabetic retinopathy, Inflammation, Microglia, Pericyte, Somatostatin
Diabetic retinopathy (DR) is a complication of diabetes, caused by high blood sugar levels damaging the retinal microvasculature. Mechanisms, such as oxidative stress and deposition of advanced glycation end products, leads to glial cell activation and neuronal apoptosis. Pericytes, contractile...