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Long-term effect of gene therapy on Leber’s congenital amaurosis

After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

How common is ocular trauma in children and what are the clinical features?

The authors present a multicenter retrospective case review with the aim of reporting the incidence and characteristics of paediatric ocular trauma. Records for individuals aged 18 and under with a diagnosis of globe, orbit or adnexal injury over a 10-year...

Outcomes of cataract surgery in patients with uveitis

This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...

Upper eyelid ulceration as a presenting sign of frontal sinus mucocele

Introduction A sinus mucocele is an epithelium-lined sac filled with mucus and desquamated epithelium. It forms secondary to inflammatory processes that occur in a sinus with an obstructed ostium. Predisposing conditions include previous trauma, surgery, tumours, anatomical abnormalities, and chronic...

What's trending Oct/Nov 2019

#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...

Specialty doctor interviews

I started my training as an ophthalmologist in the Wild West of Carmarthenshire where I did my first laser procedure, first phacoemulsification and first slit-lamp examination. All of these firsts were done under the tutelage of very skilled staff grade...

A three-way partnership between Nigeria, Tanzania and Northern Ireland

VISION 2020 LINKS between Western Health and Social Care Trust (WHSCT), Altnagelvin Area Hospital, Northern Ireland with first ECWA Eye Hospital, Kano, Nigeria and now also with Mbeya Referral Hospital (MRH), Tanzania, have been beneficial to all three partners. From...

21st Century retinal laser treatment in the anti-VEGF era

In today’s world, macular laser treatment has a vital role in the treatment of diabetic macular oedema (DMO). DMO is one of the most common causes of visual impairment. Despite expensive intravitreal treatment courses of anti-VEGF, many will agree that...

The All Eyes Foundation

At its core, All Eyes Foundation (AEF) wishes to help bring vision back to Iraq, and it intends to do this through ophthalmic subspecialty training, mentoring and infrastructure development. Based in Najaf, just over 100 miles south of Baghdad, the...

Transferring imaging from primary to secondary care (part 2)

Transferring clinical imaging from high street optometrists to secondary care is an increasingly requested option, especially in the context of the COVID-19 pandemic. A wide variety of solutions exist to allow this, each with their own merits and shortcomings. In...

What's trending Aug/Sep 2020

Life, at least from headlines, is certainly awakening again. #DominicCummings #Specsavers #BarnardCastleeyetest In one of the bizarre developments of #coronaviruslife, Dominic Cummings, Boris Johnson’s most senior advisor, claimed he drove to Barnard Castle from Durham to test his eyesight. He...

Katherine McVeigh

In this new section we profile creatives whose work is inspired by the eye. Since I was a child, I have enjoyed art projects. It provided me with a space for creative freedom without rules or restrictions. Unfortunately, this fell...