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Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Does a gut-eye axis exist?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does a gut-eye axis exist? Over a decade ago, the Human Microbiome Project was launched by...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Corneal thickness in patients with diabetic peripheral neuropathy

This cross-sectional study assessed corneal thickness in association with diabetic peripheral neuropathy (DPN) severity. The study also tried to identify the layer of the cornea most affected by DPN status. Performed at the University of Michigan the study included three...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

SPOKE launches Project Four Supervision Guidance

The Sector Partnership for Optical Knowledge and Education (SPOKE) has published the output of its fourth project.

The Retina International World Congress will take place in Dublin from June 5-8

The Retina International World Congress hosted by Fighting Blindness will take place in Dublin, Ireland, from June 5-8.

Ophthalmic Imaging: From Theory to current practice

Welcome to the 14th edition of the Ophthalmic Imaging Congress. This event, focused on Imaging and all its applications in ophthalmology, will allow us to reflect on the technological advances and the progress we have made. Program: - Theoretical Sessions:...

Retinal ischaemia on OCTA and diabetic retinopathy grade

The authors quite rightly point out that quantification of retinal ischaemia has the potential to serve as a biomarker for diabetic retinopathy disease progression. They set out to investigate the relationship between area of ischaemia on a swept source OCTA...

Endo-illumination-aided SB combined with IVT hyaluronate for RRD

The authors report a retrospective non-randomised control trial that evaluated the efficacy and safety of 25-gauge illumination-aided scleral buckling (SB) combined with hyaluronate injection for the treatment of rhegmatogenous retinal detachment (RRD). Forty-five cases were included in this study. Twenty-five...

Effects of phacoemulsification on IOP and drug use in glaucoma

For patients with comorbid cataract and primary open-angle glaucoma (POAG), guidance is lacking as to whether cataract extraction and traditional filtering surgery should be performed as a staged or combined procedure. Achieving this guidance requires an evidence-based understanding of the...

Secondary iris-claw anterior chamber lens implantation in patients with aphakia without capsular support

This retrospective, non-randomised, non-comparative, interventional study including 128 eyes of 124 patients that presented with aphakia with no capsular support. All patients consecutively underwent Artisan iris-claw intraocular lense (IOL) implantation between 1997 and 2010. The inclusion criteria were: aphakic without...