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PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Could midbrain volume on MRI be used to guide diagnosis of progressive supranuclear palsy?

The authors present a cohort study, of patients with a likely diagnosis of progressive supranuclear palsy (PSP) using a combination of prospective assessment and retrospective review. The cohort comprised of 14 patients; the data for six patients was obtained through...

Pulling on the heart strings: ophthalmologist fundraises for GOSH

NIHR Doctoral Fellow Sohaib Rufai is sharing his guitar performances to raise money for Great Ormond Street Hospital Children's Charity.

Early diagnosis of pituitary apoplexy using combined MRI findings

The author presents a literature review searching the terms ‘pituitary ring sign’ and ‘sphenoid sinus mucosal thickening’ in the context of pituitary apoplexy from 1990 until the present day. These two findings are both magnetic resonance imaging (MRI) signs of...

Neuro-ophthalmological symptoms in patients with cerebral venous sinus thrombosis

The authors of this article have evaluated the neuro-ophthalmological symptoms of 49 patients with cerebral venous sinus thrombosis. They have evaluated the onset of the disease as well as the symptoms reported. The authors present extensive clinical information for individual...

A case report of cavernous sinus syndrome following dental procedure

This case report describes a patient presenting with painful diplopia as a consequence of root canal dental treatment. Following root canal treatment a non-resolving tooth pain led to a decision to extract the tooth, leading to onset of severe periorbital...

A case of ipsilateral fourth nerve paresis and Horner’s syndrome

The author presents a single case report of an exceptional association between fourth nerve palsy and ipsilateral Horner’s Syndrome. The case is presented alongside magnetic resonance images (MRI) which reveal a mass in the right cavernous sinus. The 54-year-old woman...

Book Competition - Update: Student and Trainee Discount Available

Following the successful book competition held by Eye News, where entrants competed to win a signed copy of a book, students and trainees can now purchase a copy at a discounted rate.

CHEC Announces Collaboration with Award-winning Eyecare Company

Leading ophthalmologist Nikolina Budimlija to host CPD event in early October. Collaboration with family run Scope Eyecare reflects CHEC’s continued expansion of services and expertise.

Low Vision Questionnaire

Participation in this survey is greatly appreciated and will help eyecare practitioners to provide the support patients with vision loss deserve.

Thrombophilia in patients with retinal vein occlusion

The authors present a retrospective study of the prevalence of thrombophilia in patients with retinal vein occlusion. The study cohort included 88 patients with central retinal vein occlusion (CRVO), 51 patients with branch retinal vein occlusion (BRVO) and 40 controls....

CD40L activation of human RPE cells

Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...