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Long-term effect of gene therapy on Leber’s congenital amaurosis

After reporting the first successful gene therapy results for RPE65 deficiency in three patients in a brief report in 2008, the same team from London now report the results of 12 patients followed up for three years after transfection. As...

Are retinal vein occlusions seasonal? And if so why might that be?

Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...

Association between serum triglycerides and pan retinal photocoagulation in type 1 diabetes

This retrospective cohort study aimed to examine whether dyslipidaemia is a risk factor for progressing to proliferative diabetic retinopathy (PDR) and consequently requiring pan retinal photocoagulation (PRP) treatment in type 1 diabetics. In previous studies including the ETDRS study an...

What's trending Aug/Sept 2019

#puppydogeyes Who can resist a pair of puppy dog eyes? It may be that no human can! A team of researchers discovered that dogs acquired a new forehead muscle, which is scanty or absent in wolves. This muscle is the...

Interspecialty referrals

Referrals between the many and varied branches of ophthalmology sometimes underline how sub-specialised we have all become nowadays. The old era when everyone was an ophthalmic jack of all trades is gone, for better or for worse, and instead of...

A step-by-step approach to the diagnosis and management of Sands of Sahara Syndrome

Sands of Sahara syndrome (diffuse lamellar keratitis) is a rare postoperative complication of Laser in situ keratomileusis (LASIK). Its estimated prevalence is reported to be 2-4% among LASIK cases [1], despite that, it is more likely to be encountered by...

Glucose-sensing contact lenses replace the finger prick test!

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: Glucose-sensing contact lenses replace the finger prick test! The concept of contact lenses was first illustrated by...

Does beauty truly lie in the eye of the beholder?

Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Does beauty truly lie in the eye of the beholder? Scleral whitening, iris colour-changing drops and...

RCOphth 2024 Preview

Here is our annual highlights preview of the upcoming RCOphth 2024 Annual Congress in Belfast's ICC, 20-23 May.

It’s easy when you know the rules

As I was travelling along a deserted road on a Sunday last month I saw in my peripheral vision a disconcerting flash of light behind me. Much as I tried to convince myself that the flash was due to the...

Informed consent – the Brexit test

The Medical Defence Union (MDU) runs courses on various medicolegal topics. I would guess people only ever attend these courses if they have an exam or an interview approaching as the subject matter is exceedingly dry for clinicians. I myself...

Turn up anytime

When I was starting off in ophthalmology my then boss had a standard spiel after completing a cataract case. It did not vary and I do not recall an instance of it not taking place. “The operation went well and...