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Reduced blood flow and age-related macular degeneration
This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...
Presenting and diagnostic signs of retinoblastoma
This study revisits the presenting signs of retinoblastoma (RB) in the context of current best practice with respect to diagnosis and assessment of RB. This was a retrospective review of 131 consecutive cases, excluding those with positive family history over...
Neuro-ophthalmology consequences of Lyme disease
This study sought to review the seasonality and the occurrence of Lyme disease within their institution with a focus on neuro-ophthalmic consequences. This was a retrospective study of 212 children: 50 (24%) with neuroborreliosis (NB). There was an increase in...Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...
Macular thickness after strabismus surgery
The aim of this study was to determine whether strabismus surgery is associated with changes in macular thickness as detected by OCT. The study included 60 eyes of 30 patients with mean age of 28.9±14.2 years undergoing unilateral surgery. Mean...
Intravenous paracetamol in orbital surgery
This is a large prospective study of the effect of intravenous acetaminophen (paracetamol) in orbital surgery. The study included three groups of 50 patients. One group had no i.v. paracetamol, the second 1g of i.v. paracetamol within 30 minutes of...
Methotrexate and mycophenolate mofetil for non-infectious uveitis
This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...
IO overaction surgery
This study aimed to compare the effectiveness of two surgical methods on the correction of inferior oblique overaction (IOOA). This was a retrospective study of 99 eyes of 56 patients; 47 myectomy and 52 anterior transposition procedures. Mean age was...
Strabismus measurement comparisons
The authors conducted a prospective study to compare the measurements obtained by objective alternate prism and cover test (PCT) and the subjective red glass test in 72 patients aged 60 years on average and with a mean visual acuity of...
MRI in anisometropic amblyopia
This study recruited patients with anisometropic amblyopia in the right eye and without strabismus. This allowed the authors to reduce the effort exerted in cortex activities by different amblyopic eyes. They used whole brain analysis to find the differences between...
The impact of collagen crosslinking on keratoplasty numbers in keratoconics
A question of corneal cross-linking (CXL) reducing keratoplasty numbers in keratoconics was addressed in this single centre observational study from the Oslo University Hospital – a sole provider of keratoplasties and CXL for a population of 2.8 million. Authors compared...
