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Neuroanatomical structures and eye movements

The aim of this study was to review and critically discuss the role of ocular proprioception in oculomotor control and development of eye motility disorders. The authors considered proprioception, structure and proprioceptors of eye muscles, singly and multiply innervated muscle...

Longitudinal changes in axial length in high myopia

This is a prospective, longitudinal, observational single centre study between May 2011 and September 2018, to determine the changes in the axial length (AL) longitudinally in patients with high myopia without other conformational abnormalities. Patients were divided into two groups:...

OCT biomarkers in asymmetric anti-VEGF response in bilateral diabetic macular oedema

This study aimed to identify optical coherence tomography (OCT) biomarkers for predicting response to anti-VEGF treatment in diabetic macular oedema (DMO). Bilateral DMO patients with asymmetric response to a loading dose of anti-VEGF (ranibizumab / aflibercept) treatment were retrospectively studied....

Diplopia after cataract surgery – risk factors

The risk factors for binocular diplopia after uncomplicated cataract surgery in adults were studied to analyse the patterns of ocular motility and clinical causes. This was a retrospective review of 40 patients; 25 female. Onset of diplopia was at a...

Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

Silicone hydrogel contact lenses versus autologous serum drops for dry eyes in Sjörgen syndrome

A total of 37 patients with Sjörgen syndrome (SS) related dry eyes reporting symptoms on standard therapy with artificial tears and anti-inflammatory drops were evaluated in this trial. They were randomly assigned to additional treatment with either balafilcon A silicone...

Management of diffuse OSSN with topical chemotherapy

Ocular surface squamous neoplasia (OSSN) can be localised to the conjunctiva or, less commonly, diffusely spread over the conjunctiva and cornea. Localised OSSN can be treated by surgical removal with adjuvant cryotherapy and chemotherapy with low rates of recurrence. Diffuse...

Aqueous humour cytokine levels in PCV and nAMD

This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...

Antibiotic prophylaxis after intravitreal injections

The use of topical antibiotics as prophylaxis after intravitreal injections is a contentious issue, especially now with increasing use of intravitreal anti-VEGF agents. In the Wills Eye Institute, prior to May 2011, all patients undergoing intravitreal injections in the office...

Direct endoscopic probing for congenital lacrimal duct obstruction

The most common treatment for congenital lacrimal duct obstruction (CLDO) is probing, which is traditionally a blind procedure. Previous literature reports success rates between 78-92%. The authors of this retrospective non comparative case series reviewed the success rates of probing...

An update on idiopathic intracranial hypertension

The incidence of Idiopathic intracranial hypertension (IIH) is increasing, likely in line with the worldwide epidemic of obesity. To date, there have been revisions in the terminology used and diagnostic criteria for IIH; these recognise the need to exclude secondary...

In conversation with Iqbal K Ahmed - From across the Atlantic

Ike (Iqbal) K Ahmed is a pioneering ophthalmologist from Canada, currently serving as Assistant Professor at the University of Toronto, and Clinical Assistant Professor at the University of Utah. He is also the Research Fellowship Director, Department of Ophthalmology, University...