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Discussing treatment modalities for bilateral wet AMD
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....Binocular single vision (BSV)
Introduction In this article I will try to summarise some of the definitions, tests and assessments performed in the strabismus clinic to assess patient binocular potential. This is a key feature of strabismus assessment, especially in adults, and it will...Corporate M&A pace gathers momentum
Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...
Ocular manifestation of Marfan Syndrome
This repeated cross-sectional study collected data in 2003-2004 and 2014-2015 to investigate changes in ocular features in Marfan syndrome (MFS) fulfilling the Ghent-2 criteria. Ghent-2 is a set of criteria by which MFS are identified and includes aortic root aneurysm...
Glaucoma and capillary perfusion
Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...
Colour Doppler imaging before and after orbital decompression in thyroid eye disease
In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...
Migraine attack: does retinal and peripapillary blood flow change?
This prospective clinical study compared retinal and peripapillary blood flow parameters in migraine patients during an attack with healthy controls using optical coherence tomography angiography (OCTA). OCTAs were performed on 52 eyes from 26 migraine sufferers and 48 eyes from...
Microperimetry measurements in anisometropic amblyopia
The authors aimed to evaluate retinal sensitivity and fixation characteristics in children with anisometropic amblyopia by macular analyser integrity assessment (MAIA) microperimetry and to compare the results between amblyopia and fellow eyes. The study included 39 children; 21 female –...
Changes in drusen and retinal layer volumes prior to CNV development
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
What is paracentral acute middle maculopathy?
This is a review article characterising a clinical entity called paracentral acute middle maculopathy (PAMM). The article highlights the fact that retinal capillary plexuses are organised predominantly into three trilaminar capillary layers occupying the area between the nerve fibre layer...
Cystoid macular oedema following retinal detachment surgery
There are limited studies examining the incidence and risk factors for postoperative cystoid macular oedema (CMO) following rhegmatogenous retinal detachment (RRD) repair. Postoperative CMO is thought to be due to pro-inflammatory state, where numerous cytokines lead to tight junction dysfunction,...
