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Effect of preservative free fluoroquinolones on human corneal epithelial cells in vitro

1 October 2014 | | Cornea / External Eye Disease
Fluoroquinolones, including second generation (ofloxacin and ciprofloxacin), third generation (levofloxacin and tosufloxacin) and fourth generation (gatifloxacin and moxifloxacin), are a group of bactericidal agents used to treat multiple ocular infections. The third and fourth generation fluoroquinolones have enhanced Gram-positive activity...

Autophagy in lens mitochondria loss

1 April 2014 | | Cataract and Refractive | ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Modern trabeculectomy outcomes

1 February 2014 | | Glaucoma
This audit was conducted by the Trabeculectomy Outcomes Group Audit Study Group to report on the efficacy and safety of current trabeculectomy surgery in the UK. This is relevant in light of the fact that the trabeculectomy outcomes presented by...

Macular oedema after cataract surgery in diabetic patients

1 December 2013 | | Retina / Uvea / Vitreous
The authors describe a multi-centre prospective observational study of 293 participants that underwent cataract surgery who all had diabetic retinopathy without definite central-involved macular oedema. Forty-five clinical sites took part throughout the United States. Patients were eligible if there was...

Meltdown, Spectre, Flying Hospitals and Spy Cams

1 April 2018 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
iPhone slowdown In early 2018 users discovered that Apple was slowing down older iPhones intentionally. The reported reason was to prolong the usable battery life. These changes were made without the knowledge or consent of owners. Unsurprisingly, a community backlash...

What's trending Jun/Jul 2019

1 June 2019 | Ophthalmology
#beeping #EasterEgg Beeping Easter eggs allow blind and visually impaired children to participate in the quintessential Easter activity for children – the Easter Egg Hunt. It kind of takes the fun out of the hunt if you need to be...

Twenty-five years in retina

1 February 2019 | | Ophthalmology, Retina / Uvea / Vitreous
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...

It’s Friday, I’m In Love: Pete’s Hidden Curriculum Part 3

3 February 2023 | | Ophthalmology
“When you’re in love, it’s the most glorious two-and-a-half days of your life.” - Richard Lewis [1]. The good news is that we are over the hump now and past the most depressing day of the year, which is known...

In conversation with Christopher Liu OBE

1 June 2018 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Oculoplastics, Ophthalmology, Optometry, Ocular Pathology and Oncology, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Eye News caught up with Christopher Liu following his recent appointment by Her Majesty Queen Elizabeth II as an Officer of the Most Excellent Order of the British Empire for Services to Ophthalmology. Christopher Liu OBE. Congratulations on your recent...

A case of Miller Fisher Syndrome and bilateral asymmetric globe retraction

1 February 2022 | | Ophthalmology, Neuro-Ophthalmology
Miller Fisher syndrome (MFS) is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It was first recognised by James Collier in 1932 as a clinical triad of ataxia, areflexia and ophthalmoplegia. Later, it...

The challenge of chorioretinal folds in virtual eye clinics

3 June 2024 | | Retina / Uvea / Vitreous, Orbit
Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

On the wrong track

1 June 2015 | | Cataract and Refractive, Imaging, Ophthalmology, Retina / Uvea / Vitreous
A 65-year-old very high myope lady presented with sudden blurred vision down to count fingers to her right eye after a short and sharp pain. She also described seeing a black swirly line and as all these symptoms were exactly...