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Comparison of retinal pigment epithelium-choroid graft surgery and anti-VEGF therapy in patients with wet AMD

1 December 2015 | | Retina / Uvea / Vitreous
This was a randomised intervention study in wet AMD patients to investigate benefits of free RPE-choroid graft transplantation surgery versus (continuation of) anti-VEGF treatment. Twenty patients who met the inclusion criteria were subdivided into three subgroups, i.e. RPE tears involving...

RaScaL Study

1 June 2015 | | Retina / Uvea / Vitreous | Diabetic macular edema, Fluorescein angiography, Anti-VEGF, Ranibizumab, Laser photocoagulation, Combination therapy, Optical coherence tomography
The RaScaL study was a six month, single-centre, controlled, prospective phase I/II study in which subjects with diabetic macular oedema (DME) and associated peripheral nonperfusion on ultrawide-field fluorescein angiography (UWFA) were randomised to: (1) study arm: ranibizumab (0.5 mg) injection...

What’s Eating Gilbert Pete

2 August 2022 | | Ophthalmology
“Please phone Mr C Lyon ASAP on 0131 334 9171” This was a message from my secretary waiting for me on my computer one morning shortly after I was appointed a consultant. The name did not ring any bells but...

Precision and accuracy of TearLab osmometer

1 February 2015 | | Cornea / External Eye Disease | Dry-eye disease, in situ osmometer, tear osmolarity
Measuring tear osmolarity has been identified as a potential method for objectively diagnosing dry eye. TearLab osmolarity system is an in situ osmometer which may be a promising candidate for clinical use as it is portable and only requires a...

A career in uveitis

7 December 2020 | | Ophthalmology, Retina / Uvea / Vitreous
As he retires from clinical practice, the author looks back on his long career in uveitis and how care of these patients has changed dramatically since his days as an undergraduate. My trainees and fellows are often bored by my...

Insights on medical AI for ophthalmology: an update on current perspectives

3 June 2024 | | Ophthalmology
Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

Prevalence of acute anterior uveitis in diabetic patients attending diabetic eye disease clinics

5 April 2022 | | Ophthalmology, Retina / Uvea / Vitreous
The authors share their investigation at Manchester Royal Eye Hospital into the association between diabetes and AAU. The global prevalence of diabetes mellitus (DM) is rapidly rising from an estimated 9.3% in 2019 to 10.2% by 2030 [1]. The link...

Competition ratios: Is the future of ophthalmology too bright?

29 August 2023 | | Ophthalmology, ONLINE EXCLUSIVE ARTICLES
In the UK, ophthalmology is a highly competitive speciality, attracting many medical graduates keen to pursue a career in this area. However, in recent years, the competition ratios for ophthalmology ST1 training posts have increased significantly, creating a challenging environment...

What's trending Aug/Sep 2020

5 August 2020 | | Ophthalmology, Emergency Ophthalmology, Optometry
Life, at least from headlines, is certainly awakening again. #DominicCummings #Specsavers #BarnardCastleeyetest In one of the bizarre developments of #coronaviruslife, Dominic Cummings, Boris Johnson’s most senior advisor, claimed he drove to Barnard Castle from Durham to test his eyesight. He...

A brief history of colour vision

1 April 2019 | | Ophthalmology, Optometry
Andrew Want takes a look at how colour vision has evolved in humans and animals and how it differs across species. Colour vision is something that we often take for granted, but it has become so intrinsic to the way...

The Real Top Gun: Professor Steve Schallhorn

3 April 2023 | | Ophthalmology
Steve Schallhorn: Fighter Pilot. In the spring of 1987, I travelled to the cinema at Hendon Central in London with some school friends to watch the newly released movie The Witches of Eastwick starring Jack Nicholson and Michelle Pfeiffer. Unfortunately...

The International AMD Genomics Consortium study: another success in understanding the complex genetics of AMD

1 April 2017 | | Genetics
Age-related macular degeneration (AMD) is a neurodegenerative complex disease of the eye and a major cause of blindness and visual impairment among the elderly worldwide. The early stages of the disease are characterised by asymptomatic pigmentary abnormalities and accumulation of...