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Infliximab in treatment of PVR
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
How the thinking machine is transforming the retinal landscape
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...Mastering clinical skills in ophthalmology
To young junior doctors, and some senior doctors who may not have had much exposure to ophthalmology, the specialty can seem very foreign. Not only are the conditions and examination findings specific to the eyes, but the skill set required...Discussing treatment modalities for bilateral wet AMD
A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....
Light reflex in preterm infants
In this study, the pupillary size and light reflex was examined in premature infants using infrared video-pupillography and stimuli of red and blue light. Only eyes of infants without retinopathy of prematurity were included in the study. Pupillary light reflexes...Corneal hysteresis: An emerging biomarker in the management of glaucoma
Corneal hysteresis (CH) is gaining recognition as a valuable parameter in the management of glaucoma. Corneal hysteresis is defined as the difference between the inward and outward pressure responses of the cornea during deformation. This measurement reflects the viscoelastic properties...Videos - iStent Inject
Trabecular bypass surgery with iStent Inject enhances aqueous outflow from the eye , evidence of this is demonstrated through Angiographic visualization of aqueous humor outflow in studies conducted by Dr. Alex Huang M.D, Ph.D
Ocular ischaemic syndrome in a rat model
Ocular Ischaemic syndrome is a devastating eye disease caused by severe carotid stenosis. This study’s purpose was to develop a reliable rat model for this syndrome by subjecting rats to common carotid artery occlusion and sham surgery. Rats were assigned...
Diagnosis and management of orbital vascular malformations
This is an authoritative review of a controversial and difficult clinical area. The authors have experience of over 350 cases and provide a well-structured review of the classification and management of orbital vascular malformations. They emphasise the need to understand...
An unusual case report of bilateral abducens paralysis
In this case report a nine-year-old girl develops bilateral abducens nerve paralysis, caused by vertebrobasilar dolichoectasia. Vertebrobasilar dolichoectasia is characterised by dilation, tortuosity and marked elongation of the vertebral and basilar arteries. Clinical findings result from the compression and displacement...
Lacquer cracks
The purpose of this Japanese study was to analyse the morphologic features and natural progression patterns of lacquer cracks (LC). The presence of linear hyperfluorescence on the fundus fluorescein angiography (FFA) was used as the standard for diagnosing the presence...
