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New mouse model of diabetes mellitus

1 April 2014 | | Retina / Uvea / Vitreous | aldose reductase, cell signaling P-ERK1/2, P-SAPK/JNK, P-Akt, diabetic rats, diabetic retinopathy, green fluorescent proteins, growth factors VEGF, bFGF, TGF-β, retinal vascular changes, transgenic diabetic mouse models
Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy

1 February 2014 | | Glaucoma
Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...

Effective management of dry eye and ocular surface disease

4 August 2021 | | Ophthalmology, Optometry
Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

Cataract incidence rates in patients from the UK suffering with diabetes mellitus

1 October 2018 | | Cataract and Refractive, Ophthalmology
The authors summarise the main findings from a recent study which investigated the incidence rates of cataract in patients with or without diabetes mellitus (DM). Background to the study Worldwide, the World Health Organization (WHO) estimates that 253 million people...

What’s new in wet AMD papers?

1 December 2016 | | Retina / Uvea / Vitreous
Paper presentations on neovascular (‘wet’) age-related macular degeneration (AMD) from the 16th European Society of Retina Specialists Congress, Copenhagen, September 2016, outline recent research directions evaluating the impact of vision loss on key health domains, patient preferences in the process...

Ophthalmic mentors: Professor Carrie MacEwen

1 February 2015 | | AMD, Cataract and Refractive, Cornea / External Eye Disease, Emergency Ophthalmology, Genetics, Glaucoma, Imaging, Neuro-Ophthalmology, Ocular Pathology and Oncology, Oculoplastics, Ophthalmology, Optometry, Orbit, Paediatric Ophthalmology / Strabismus, Retina / Uvea / Vitreous
Caroline (Carrie) MacEwen is a Consultant Ophthalmologist at Ninewells Hospital and Medical School, Dundee, and Head of the Ophthalmology Department at the University of Dundee (Honorary Professor). She trained in Glasgow, Dundee and London. Carrie took over as President of...

Pharma chameleon

3 April 2024 | | Ophthalmology
One morning in September ’95, about a month into my first house job on the South Coast of England, I emerged from the ridiculously early ward round on the coronary care unit feeling a bit dazed and therefore headed off...

The International Centre for Eye Health: weaving the global threads together

4 October 2023 | | Ophthalmology
The VISION 2020 LINKS & Networks Programme has been writing regular articles in Eye News about its capacity-strengthening activities in low- and middle-income countries (LMICs) for more than a decade. This, the first International Issue, is a landmark for Eye...

Orbis teams up with the Alcon Foundation and OMEGA to improve eyecare in Zambia

29 September 2023 | orbis, Flying Eye Hospital, alcon, OMEGA, Zambia, Africa
The Orbis Flying Eye Hospital returns to Zambia for a three-week training project in Lusaka coinciding with World Sight Day on October 12.

In conversation with Charles Leclercq (ARxVision)

5 October 2022 | | Ophthalmology, ONLINE EXCLUSIVE ARTICLES
Julian Jackson (Founder and Director, VisionBridge) spoke to Charles Leclercq (CEO, ARx) about the ARxVision, a wearable device that captures the world around us through audio and artificial intelligence to empower blind and low-vision individuals. You can read the Eye...

How effective is nurse-led telephone preassessment for cataract surgery?

25 July 2023 | | Cataract and Refractive, ONLINE EXCLUSIVE ARTICLES
Cataract surgery is the most frequently performed surgical procedure in the UK [1]. The demand for cataract surgery is projected to increase with ageing population, and the recent pandemic has further contributed to the extended waiting times in the UK....

International medical graduates in ophthalmology

4 December 2023 | | Ophthalmology
IMGs in the NHS The General Medical Council (GMC) defines an international medical graduate (IMG) as someone who has obtained their primary medical qualification outside the European Economic Area (EEA) [1], meaning that an IMG is a medical doctor whose...