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Investigating MOG-IgG as a cause for optic perineuritis
Optic perineuritis can be a manifestation of infectious and systemic inflammatory disorders, but in most cases is considered idiopathic. Diagnosis is established by magnetic resonance imaging (MRI) with the demonstration of optic nerve sheath enhancement with sparing of the optic...
Examination of optic disc drusen using computer-based fundus analysis
This case-control study analysed the optic disc angioarchitecture in optic disc drusen (ODD) using computer-based fundus examination. A group of ODD patients were compared to a group of healthy controls with normal optic discs. The cohort included 30 healthy volunteers...
Mechanism of colour vision involvement in multiple sclerosis
There is evidence to show that the optic nerve and retina are affected in multiple sclerosis (MS) even without any clinical evidence or history of optic neuritis (ON). MS without optic neuritis causes colour-vision deficit, however, the evidence for selective...
Saccadic eye movements in young-onset Parkinson’s disease
The objective of this study was to understand control of saccadic eye movements in patients with young onset Parkinson’s disease (YOPD) where onset of disease symptoms appears early in life (<40 years of age). Functional magnetic resonance imaging (fMRI) was...
Ocular adnexal marginal zone b-cell lymphoma
This is a multicentre retrospective study of seven eye centres of 689 patients with ocular adnexal extranodal marginal zone b-cell lymphoma (OA-EMZL). The median follow-up time was 42 months and the median age was 62 years. Fifty-five percent were women;...
Support for patients with nystagmus
This is a qualitative study in patients with nystagmus identified through regional clinics, charity events and the Royal National Institute of Blind People (RNIB). Two hundred and fifty-one participants were identified, with 184 respondents included in the study. Fifty-six percent...
Mediation of vertical vergence
The authors hypothesised that if vertical vergence were mediated by vertical rectus muscles, then the eye that moves during a vertical fusion task would produce larger vertical vergence when abducted versus adducted. Similarly, if mediated by the oblique muscles then...
Lang Stereopad comparisons
The aim of this study was to compare the effectiveness of the Lang Stereopad in detecting and measuring stereopsis in a population with normal visual parameters. The Lang Stereopad was compared directly to the Frisby, TNO and Lang II stereotests...
CD73 in aggressive basal cell carcinoma
This is a retrospective review looking at levels of CD73 in aggressive basal cell carcinomas (BCCs) that invade the orbit. Eleven patients who underwent orbital exenteration for invasion by BCCs were compared with 10 matched controls who had simple nodular...
Duane’s retraction syndrome (DRS)
The authors aimed to review all cases of DRS presenting to a tertiary paediatric eye clinic in South Africa during a 20-year period. This was a retrospective study in Cape Town involving 120 patents (80 mixed race, 24 black and...
Surgical results in spinocerebellar ataxia (SCA)
Patients with SCA frequently develop ocular motility abnormalities including nystagmus, abnormal smooth pursuits, dysmetric saccades, divergence paresis and ophthalmoplegia. Incidence of diplopia is higher in SCA type 3. The purpose of this study was to evaluate surgical responses and outcomes...
