You searched for "pathology"

973 results found

Conjunctival inflammation in glaucoma patients

Numerous studies have demonstrated that topical medications and preservatives used for the management of glaucoma can induce significant histopathologic and inflammatory changes in the ocular surface. This study describes an increased expression of major histocompatibility complex class II antigen HLA-DR,...

Comparison between findings in ‘active’ or ‘healed’ giant cell arteritis

Giant cell arteritis (GCA) is the most common systemic vasculitis in older people and can cause devastating sight loss if untreated. Temporal artery biopsy is often relied upon for diagnosis by ophthalmologists, with a positive biopsy result indicating whether the...

Reduced blood flow and age-related macular degeneration

This was a prospective cross-sectional study assessing changes in blood flow velocity in patients with age-related macular degeneration (AMD) using a retinal function imager. Sixty eyes with wet AMD were compared to 53 control eyes and the average blood flow...

Higher risk of poor functional outcome in the presence of visual deficits post-stroke

The authors present a retrospective case review with the aim of reporting the disability outcomes of individuals 90-days post stroke with and without visual deficits. The Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke (HOPES) Registry was used as the...

Does Duane syndrome have an effect on refractive error?

The authors present a retrospective case review from a database created from a 43-year period of patients with strabismus seen by a single ophthalmologist. Cases were reviewed by either an orthoptist or ophthalmologist for entry into the database. Details relating...

Referral patterns and pathways for intracranial hypertension

The authors present a retrospective case review of individuals with suspected raised intracranial pressure (ICP) over a 12-month period a single tertiary neuro-ophthalmology centre. Cases were categorised into four groups based on examination by neuro-ophthalmology; 1) referred after identification of...

Age-related distance esotropia – what are the clinical characteristics?

The authors present a retrospective case review of individuals with primary divergence insufficiency or age-related distance esotropia, over a 15-year period. Inclusion criteria allow for the difference between near and distance angles to be patient reported or objectively measured. One...

Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)

The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...

Educational concerns and anxiety levels amongst ophthalmology trainees during the COVID-19 pandemic

How concerned are ophthalmology trainees about the present impact and the future consequences of suspended ophthalmic training programmes? Researchers in the West of Scotland investigate. Anxiety, stress and the longer-term stress reaction of burnout often go unrecognised, yet are known...

The original smooth operator: Sir Robin Millar

As an early 80s kid, if you lacked sufficient pocket money, building a music collection entailed recording your favourite songs off the radio with a cassette deck and hoping the presenter didn’t interrupt at any point, with a finger hovering...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Ophthalmic Aid to Eastern Europe (OAEE)

Peter Cackett, Tim ffytche and Dr Irina Gout reflect on historic ophthalmic aid sent to Eastern Europe. This article was written prior to the horrific events in Ukraine. An appeal for funds and equipment may be made by OAEE later...