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Intensive diabetes therapy and ocular surgery in type 1 diabetes
The Diabetes Control and Complications Trial (DCCT) ran between 1983 and 1993 and showed that intensive glycaemic control was beneficial in reducing diabetic retinopathy in type 1 patients. There was a 76% reduction in onset of retinopathy and a 52%...
Inner nuclear layer of the retina showing increase in thickness in diabetic macular oedema
Diabetic retinopathy is one of the leading causes of blindness in the developed world. With optical coherence tomography (OCT), it has become possible to image the retina in vivo and to measure retinal oedema by measuring retinal thickness (RT) with...
Results after 1.4mm biaxial cataract surgery and implantation of a new aspheric intraocular lens
The aim of this study was to analyse the clinical outcome and higher-order aberrations (HOAs) after 1.4mm biaxial micro incision cataract surgery (B-MICS) and implantation of a new aspheric intraocular lens (IOL). A total of 157 eyes of 106 patients...
What are the features of facial nerve palsies in children?
The aim if this study was to report ophthalmic related findings and complications in children with facial palsy. Medical records from a tertiary centre were retrospectively searched for children 16 years and under with a diagnosis of facial palsy, over...
Saccades and contrast sensitivity in retinoblastoma survivors
The authors report a cross-sectional study, which recruited children aged 5 to 18 years old who completed treatment completion for retinoblastoma more than six months ago. Exclusion criteria included bilateral enucleation and pre-existing conditions associated with cognitive impairment. A total...dry eye 2023
To skip directly to features, click the links below: Welcome from the editor - by Andrena McElvanney The role of meibomian gland dysfunction in evaporative dry eye - by Sai Kolli Effective management of dry eye and ocular surface disease...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Aqueous humour cytokine levels in PCV and nAMD
This study looks into the possible roles of various cytokines or growth factors in the pathogenesis of exudative age-related macular degeneration (AMD) by comparing aqueous levels of 14 cytokines between eyes with polypoidal choroidal vasculopathy (PCV) and those with neovascular...
Outcomes of cataract surgery in patients with uveitis
This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...
Ovarian hormones drive onset of Sjogren’s disease in mice
Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...
Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
