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High quality retinal image grading and management service by the NetwORC UK
In 2004 a network of three ophthalmic reading centres in Belfast, London and Liverpool (known as NetwORC UK) was established to form the largest reading centre in Europe for the purpose of providing high quality grading of ophthalmic images for...Understanding and confronting bacterial endophthalmitis
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...Innovations in ophthalmology: what can the innovations of the past teach us about tomorrow?
BUOS Prize Essay – 2nd prize winner for 2013 submissions Introduction An essay titled Innovations in Ophthalmology might choose to focus on the history; from cataract couching to femtosecond lasers, ophthalmology has had no shortage of topics worthy of discussion....Sustainability in eyecare: Aravind Eye Hospital’s low carbon eyecare system
The field of healthcare has a substantial impact on the environment as it is responsible for 5-10% of greenhouse gas emissions and 9% of air pollutant generation [1]. Surgery is associated with the rapid consumption of single-use products and waste...Sexually transmitted conjunctivitis – the REALLY sticky eye
Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...Simulated ocular surgery
See also Simulated ocular surgery - strabismus surgery and Simulated ocular surgery: pars plana vitrectomy and scleral buckling surgery This is the first of a series of articles that will have three aims. Firstly, to demonstrate why simulated ocular surgery...Exploiting nature’s randomised trials of eye disease
Confounding and reverse causation in observational ophthalmic epidemiology Traditional observational studies are inherently limited in establishing a causal effect of an exposure on an outcome of interest. One fundamental limitation is confounding, whereby causation is incorrectly attributed to a third...
RTP801 as a neuroprotective and axon regenerative treatment
This paper describes the neuroprotective and axon regenerative effects of siRTP801, which is a translatable small-interfering RNA (siRNA) targeting mTOR negative regulator; RTP801, through in-vivo and in-vitro models. In-vivo studies involved an optic nerve crush rat model with intravitreal injections...
Outcomes of cataract surgery in patients with uveitis
This is a systematic, evidence-based literature review and meta-analysis, looking at the visual outcomes (vision 20/40 or better) of cataract surgery in uveitic eyes. The authors searched MEDLINE, EMBASE, CINHAL and CENTRAL, including English language and human studies only. They...
Customised orbital implants
This is a literature review of the outcomes of orbital fracture repairs using custom-made orbital implants. Customised implants were manufactured in one of three ways, all using a 3D printer; manual moulding of an implant based on a 3D-printed model...
Submacular haemorrhage associated with nAMD: A meta-analysis and meta-regression on use of tPA and anti-VEGFs
The aim of this study was to evaluate the efficacy of a combination of tPA and anti-VEGF in the treatment of submacular haemorrhage (SMH) associated with neovascular age-related macular degeneration (nAMD). A systematic review meta-analysis following PRISMA guidelines, focusing on...
