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A possible biomarker for diabetic retinopathy
Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...
Myopathic ptosis and lower lid retraction surgery
This is a description of a surgical technique which simultaneously addresses both the upper lid ptosis and lower lid retraction in patients with moderate to severe myopathic ptosis. The procedure was performed on 16 eyes of nine patients and involved...
Does Acanthamoeba need bacteria to cause keratitis?
An animal study was carried out on 36 rabbits, whose corneas were inoculated with either Acanthamoeba castellanii alone, Pseudomonas aeruginosa alone or both pathogens together after a period of short (two hours) or long (six hours) co-incubation. The clinical severity...
Corneal lenticule allotransplant
This animal study looked at corneal lenticule allograft transplantation in rabbits. Seven rabbits underwent small incision lenticule extraction (SMILE) procedures, where their stromal lenticules were extracted and transplanted fresh into pre-prepared corneal stromal pockets of seven recipient eyes. Animals were...
Treatment options for septic cavernous sinus thrombosis
Septic cavernous sinus thrombosis is a rare but serious complication of infection of the cavernous sinuses. Potential therapies include antibiotics, corticosteroids and anticoagulation, as well as surgical intervention for source control of the infection. The authors report that there is...
Prevalence and related factors for strabismus and amblyopia in Africa
The aim of this study was to overview the literature in relation to strabismus and amblyopia and associated risk factors in Africa. The review included 24 papers; eight for strabismus and 21 for amblyopia. Sample sizes ranged from 352 to...
Ophthalmic presentations and outcomes in Erdheim-Chester disease
This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...
Treat and extend for PCV
This South Korean study investigated the efficacy of a treat and extend regimen (TER) using ranibizumab to treat polypoidal choroidal vasculopathy (PCV). Twenty-nine eyes were included in this retrospective case note review. Of these, five eyes had been treated with...
MISS vs. fornix approach
The objectives of this study were to compare minimally invasive strabismus surgery (MISS) with the fornix approach in paediatric horizontal strabismus surgery (<12 years) and to evaluate early postoperative inflammation, visual acuity and operating time after a four-year training period...
Platelet rich fibrin membrane for descemetocele
This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...
Systematic review on vergence neural pathways
A full systematic review of the literature was carried out by the authors, to identify literature available on vergence neural pathways and associated disorders. The review included articles related to vergence neural pathways, along with articles that discussed the anatomy,...
