You searched for "AMD"
Changes in drusen and retinal layer volumes prior to CNV development
7 April 2021
| Ed Rule
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EYE - Vitreo-Retinal
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Age-related macular degeneration, Choroidal neovascularisation type, Drusen load, Imaging biomarkers, Retinal layer volumes
This retrospective longitudinal study looked at patients with wet age-related macular degeneration (AMD) in one eye who subsequently developed wet AMD in the fellow eye. The aim was to discover whether drusen characteristics or volumes of retinal layers correlate with...
More sensitive visual acuity test for age-related macular degeneration
1 October 2016
| Roger S Anderson (Prof), Nilpa Shah
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EYE - Vitreo-Retinal
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...
The rarebit vision test for macular conditions
1 October 2015
| Nana Theodorou
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EYE - Vitreo-Retinal
Rarebit testing is used to measure low degrees of neuro-visual damage and is available for free on the internet. It consists of a fixed bright light dot presented on a black background. During testing it is presented briefly at different...
Complement factor B polymorphism and the phenotype of early age-related macular degeneration
1 August 2014
| Huw Edward Oliphant
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EYE - Vitreo-Retinal
The relationship between complement factor H (CFH) and age-related macular degeneration (AMD) is very well known, but other genetic polymorphisms relating to AMD are more poorly understood. This study was designed to investigate the relationship between complement factor B (CFB)...
HtrA1 enhances cell senescence
1 December 2013
| Graham Wallace
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EYE - Vitreo-Retinal
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
1 April 2014
| Bheemanagouda Patil
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EYE - General
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
In conversation with Professor Usha Chakravarthy (2018)
1 March 2019
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EYE - Vitreo-Retinal, EYE - General
Professor Chakravarthy popped by the Eye News stand at the 2018 Royal College of Ophthalmologists Annual Congress after her excellent Bowman Lecture. She gave us a summary of her presentation, which looked at how our understanding of AMD has changed...
Corneal crosslinking in pellucid marginal degeneration
Fourteen studies were included in this first review examining the use of corneal-crosslinking (CXL) to treat pellucid marginal degeneration (PMD). PMD is a bilateral, non-inflammatory corneal thinning disorder characterised by inferior peripheral corneal thinning 1-3mm from the limbus in the...My top five: Emerging alternatives to manage and treat nAMD
3 April 2024
| Nikhil Sharma, Paras Agarwal
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EYE - Vitreo-Retinal
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...
My Top Five: Emerging alternatives to manage and treat nAMD
3 April 2024
| Nikhil Sharma, Paras Agarwal
|
EYE - General
Wet (exudative or neovascular) age-related macular degeneration (AMD) is characterised by choroidal neovascularisation, in which new blood vessels from the choroid invade through Bruch’s membrane. These blood vessels proliferate beneath or through the retinal pigment epithelium (RPE), causing patients to...
Age-related macular degeneration
1 December 2015
| Nana Theodorou
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EYE - Vitreo-Retinal
This review article offers an up to date review of the genetic and environmental risk factors associated with aetiology surrounding age-related macular degeneration (AMD). The article briefly describes the typical clinical presentation relating to early and late stages of the...
