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Using OCT to screen and monitor Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative illness characterised by progressive decline in cognitive function. AD is the main cause of dementia worldwide. Over recent years researchers have strived to find biomarkers to diagnose AD, particularly in the early stages of...

Choroidal thickness in ocular sarcoidosis by OCT measurement

This is the first study to evaluate the choroidal thickness in patients with ocular sarcoidosis during the quiescent phase using enhanced depth imaging optical coherence tomography (EDI-OCT) and comparing with normal subjects. Ocular sarcoidosis may affect the choroidal circulation (occlusive...

Handheld OCT in children with Down’s syndrome

This article investigated the use of handheld optical coherence tomography (OCT) in children with Down’s syndrome. Fourteen children were recruited to the study with a mean age of 6 years and 10 months with 57% male. All patients were dilated....

Hyper reflective foci (HRF) on OCT in diabetic retinopathy

This study investigated the presence of hyper reflective foci (HRF) in asymptomatic patients affected by type 1 or type 2 diabetes, separately, without clinically significant diabetic macular oedema and visual impairment. In total 71 eyes with non-proliferative diabetic retinopathy were...

Scheimpflug vs. OCT in measuring corneal thickness

The authors report on the reproducibility and repeatability of corneal thickness measurements using three different Scheimpflug imaging cameras (Pentacam, Sirius and Galilei) and one Fourier-domain optical coherence tomography (OCT) system (RTvue-100). The rationale for this study is that corneal thickness...

Glaucoma diagnosis with spectral-domain OCT of GCL and IPL

This is a prospective, cross-sectional, observational study by the New York Eye and Ear Infirmary, which recruited normal subjects and glaucoma patients with a range of visual field loss representing various degrees of glaucomatous optic neuropathy. A total of 69...

Disc margin delineation using spectral domain OCT

Observing progressive anatomical changes of the optic nerve head is essential in the detection of progression in glaucoma. Imaging devices continue to evolve and are useful in detecting change in established glaucoma, although probably less useful in an initial diagnosis....

What’s trending? Oct/Nov 2017

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #NHSwaitingtimes, #NHSprivatisation, #NHSpostcodelottery The NHS in crisis seems ever topical, but this time, the focus is on long waiting times...

Fixation target position for increased limbus measurement accuracy with AS-OCT

The authors intended to determine the optimal gaze fixation points for lateral rectus and medial rectus muscle insertions using anterior segment - optical coherence tomography (AS-OCT) compared with intraoperative measurements. They recorded 46 lateral and 36 medial rectus muscles from...

OCT choroidal signs for congenital retinal pigment epithelium hypertrophy

Congenital hypertrophy of the retinal pigment epithelium (CHRPE) on ocular coherence tomography (OCT) has the characteristic sign of RPE thickening and hyper reflectivity. However, the underlying choroid characteristics remain under researched. This retrospective study utilised data from an ophthalmic oncology...