You searched for "epithelium"
Laser corneal refractive procedures – a review
Evolution of refractive surgery stays true to the quote of Theodore Roosevelt: “The more you know about the past, the better prepared you are for the future.” Refractive surgery is an evolving field, which thanks modern technologies for refining ideas...
Ginko bilboa extract affects hypoxic retinal pigment epithelial cells
1 February 2014
| Khadijah Basheer
|
Retina / Uvea / Vitreous
Wet age-related macular degeneration (AMD) is characterised by choroidal neovascular membrane (CNVM) formation. It is thought that localised hypoxia within the retina results in overexpression of growth factors such as vascular endothelial growth factor (VEGF), which induces CNVM formation. VEGF...
Troubleshooting in LASIK
Contemporary laser in situ keratomileusis (LASIK) is safe and effective. It remains the dominant intervention in routine refractive surgery for a good reason: predictable results, rapid visual recovery, and relatively simple strategies for revision treatment. Over 95% of patients are...
Limbal melanocytes and the stem cell niche
1 February 2016
| Graham Wallace
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Retina / Uvea / Vitreous
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Cell interactions, Cornea, Limbal stem cells, Melanocytes, Stem cell niche
The cornea is continually regenerated to maintain clear vision, due to a population of stem cells located in the limbal region between the cornea and the conjunctiva. These limbal stem cells (LESC) reside in crypts in structures called the Pallisades...
MicroRNAs in cataract
1 August 2016
| Graham Wallace
|
EYE - Cataract, EYE - Refractive
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Age-related cataract, Lens epithelial cells, Lgr4, MicroRNA let-7b, Ultraviolet irradiation
In an ageing population cataract formation is one of the leading causes of blindness. Cataracts are caused by a failure to clear accumulating aggregated proteins in the lens. MicroRNAs are small non-coding transcripts which bind to specific mRNAs acting at...
Autophagy in lens mitochondria loss
1 April 2014
| Graham Wallace
|
EYE - Cataract, EYE - Refractive
|
ATG5, FYCO1, FYVE and coiled coil domain containing 1, LC3B, OFZ, Pik3c3, TOM20, autophagy, autophagy-related 5, cataract, differentiation, electron microscopy, lens, microtubule-associated protein 1 light chain 3B, mitophagy, organelle free zone, phosphatidylinositol 3-kinase, catalytic subunit type 3, translocase of the outer mitochondrial membranes 20 kDa
The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...
Quiz Apr/May 2023
3 April 2023
| Christopher Bell
|
EYE - General
History A 76-year-old female presented at her local district general hospital with right decreased visual acuity, glare, and foreign body sensation, in addition to longer-term dry eyes. She was otherwise well. Her past medical history included hypertension. On examination: vision...
Myopic choroidal neovascularisation
1 August 2015
| Jonathan Chan
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Retina / Uvea / Vitreous
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Neovascularisation, Retina, Treatment Medical
This is a review article summarising the latest myopic CNV (choroidal neovascularisation) literature in the clinical experience and management outcomes for recommendation algorithm. The aetiology of the myopic CNV was discussed by the authors under the heading of the heredo-degenerative...
Long-term corneal crosslinking results in paediatric eyes
This prospective longitudinal study examined patients 18 years of age or less with progressive keratoconus, who underwent corneal crosslinking and completed 10 years of follow-up. Crosslinking protocol involved removal of epithelium, 10 minutes of riboflavin soaking, followed by 30 minutes...
Investigation into the anatomical differences of eyelashes between Caucasian and Indian specimens
This study investigated the anatomy of human eyelashes through analysis of root depth, angle, and spatial relationship. Four eyelids from Caucasian donors were obtained from fresh donors and four eyelids from Indian donors were obtained from eye bank calls. The...Apr/May 2017 Quiz
History A five-month-old baby was seen in clinic with bilateral congenital corneal opacities. The right cornea is shown in Figure 1. Figure 1. Examination revealed corneal oedema and opacities of Descemet’s membrane and endothelium with a few vesicular lesions. Corneal...
Type 3 macular neovascularisation (MNV) due to age-related macular degeneration
3 October 2024
| Sofia Rokerya
|
EYE - Vitreo-Retinal
This paper systematically reviews and summarises the current knowledge on type 3 neovascularisation due to age-related macular degeneration which is defined as neovascularisation originating from the retinal deep capillary plexus that grows towards the outer retina often penetrating the level...
