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1916 results found

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Vitreoretinal Disease: Diagnosis, Management and Clinical Pearls (second edition)

A comprehensive, well-illustrated and highly informative resource providing excellent descriptions of vitreoretinal diseases, their presentation, diagnosis and management. The 40 chapters are grouped into four sections, namely: the Anatomy and Physiology of the vitreous, retina, choroid and retinal pigment epithelium;...

The Sclera and Systemic Disorders (3rd Edition)

An interesting historical introduction captures the reader’s attention as the journey begins into exploring the peculiarities and pathologies of ‘dura tunica of Vesalius’, a term coined by anatomists of the middle ages. This refers to what we today identify as...

An alternative to povidone-iodine for intravitreal injections?

While povidone-iodine (5% aqueous) preparations have historically been considered the most effective antimicrobial prophylaxis for ophthalmic procedures and have been adopted as routine for intravitreal injections, post-procedure pain is a commonly recognized adverse event of IVI and has typically been...

5-FU in cicatricial conjunctivitis

This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...

Simulated intravitreal injection training – the way forward

Simulated surgical training is now recommended in the training curricula of all ophthalmologists in the United Kingdom [1]. Simulated training allows for familiarisation with a procedure, exercises the discipline of repetition, allows the resolution of technical difficulties and enables refinement...

Orbital filler for enophthalmos in Parry-Romberg syndrome

This is a retrospective review of three patients with enophthalmos in sighted eyes secondary to Parry-Romberg syndrome. The patients were all female, aged between 24 and 54. All three patients had 4mm of relative enophthalmos prior to treatment. They each...

Discussing treatment modalities for bilateral wet AMD

A 65-year-old lady with bilateral wet AMD and vision of 6/24 comes with an internet search about current therapies. How do you explain the various treatment modalities available? There are two NICE approved treatments for wet age-related macular degeneration (AMD)....

What's trending Oct/Nov 2020

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #oldEnglish #herbalremedies Researchers from the University of Warwick, investigating natural remedies to treat bacterial infections, have discovered a potential new treatment....

New solutions in the prevention and treatment of Acanthamoeba keratitis

The global increase in Acanthamoeba keratitis infections has emphasised the inefficiencies of current treatment and preventative methods, here researchers from the West of Scotland detail a promising new series of compounds that may stem the tide. News headlines detailing horror...

Blurred vision post liver transplant: to blame the house cat or not?

This article outlines a case of atypical ocular toxoplasmosis associated with immunosuppression. There were two potential sources of infection in this patient and we describe how we concluded which was the most likely. Case report A 33-year-old female was referred...

A comparative treatment study of VCZ and liposomal AmpB in an Aspergillus fumigatus endophthalmitis model

This study aims to compare the effects of voriconazole (VCZ) and liposomal amphotericin B (AmpB) in an experimental model of exogenous Aspergillus fumigatus endophthalmitis in a guinea pig animal model. Endophthalmitis was induced by intravitreal injection of a strain of...