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2483 results found

Intravitreal Ziv-Aflibercept: safety analysis

Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...

Moorfields implementing a non-medical intravitreal injection service

This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services. With an increasing demand in treatment for people with eye conditions such as...

Moorfields: Implementing a non-medical intravitreal injection service

This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services. With an increasing demand in treatment for people with eye conditions such as...

Moorfields: Implementing a non-medical intravitreal injection service Nov

This highly sought after intravitreal injection course has had a national and global impact by enabling numerous institutions to establish their own non-medical delivered IVT injection services.

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Methotrexate and mycophenolate mofetil for non-infectious uveitis

This is the first reported randomised clinical trial comparing methotrexate versus mycophenolate mofetil (MMF) for the treatment of non-infectious intermediate uveitis, posterior uveitis or panuveitis. To be eligible for recruitment, patients had to be on ≥15mg oral prednisone and demonstrated...

5-FU in cicatricial conjunctivitis

This is a retrospective review of 56 patients with cicatricial conjunctivitis, including 25 eyes that received sub-conjunctival injections of 25-50mg of 5-fluorouracil (5-FU) as part of their treatment. Thirty-seven patients had ocular cicatricial pemphigoid (OCP) and 19 had Stevens-Johnson syndrome...

An alternative to povidone-iodine for intravitreal injections?

While povidone-iodine (5% aqueous) preparations have historically been considered the most effective antimicrobial prophylaxis for ophthalmic procedures and have been adopted as routine for intravitreal injections, post-procedure pain is a commonly recognized adverse event of IVI and has typically been...

Simulated intravitreal injection training – the way forward

Simulated surgical training is now recommended in the training curricula of all ophthalmologists in the United Kingdom [1]. Simulated training allows for familiarisation with a procedure, exercises the discipline of repetition, allows the resolution of technical difficulties and enables refinement...

Moorfields Education: Botulinum toxin: Is it injector error, side effects or complications 2026

Moorfields Education: Botulinum toxin: Is it injector error, side effects or complications

DALK as an early therapeutic option for Acanthamoeba keratitis

Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

Orbital filler for enophthalmos in Parry-Romberg syndrome

This is a retrospective review of three patients with enophthalmos in sighted eyes secondary to Parry-Romberg syndrome. The patients were all female, aged between 24 and 54. All three patients had 4mm of relative enophthalmos prior to treatment. They each...