You searched for "inflammation"
RPE use similar pathway to regulatory T cells to inhibit immune response
Retinal pigment epithelial (RPE) cells form an important part of the blood-retinal barrier that protects the neuronal cells responsible for sight. RPE cells are involved in innate and adaptive immune responses via expression of surface molecules and release of cytokines....
Complement Factor H and Factor H-Like protein are expressed in human RPE cells
The role of inflammation in age-related macular degeneration (AMD) is well documented and the association of AMD with the inflammatory marker C-reactive protein (CRP) and members of the complement system underline the role of complements in AMD. Human complement factor...
HLA-B27 anterior uveitis
HLA-B27 has previously been shown to have an association with uveitis, ankylosing spondylitis, reactive arthritis, ulcerative colitis and psoriasis. The authors of this review provide an update of the epidemiology of HLA-B27 associated ocular disorders. There is great variation amongst...Moorfields Education International Uveitis Symposium
Don't miss this chance to hear from top national and international speakers, including symposium organiser Professor Carlos Pavesio, Consultant Ophthalmologist and uveitis specialist at Moorfields Eye Hospital and Director of the Scientific Organizing Committee. This unique three day symposium will provide a forum for the exchange of information and new ideas relevant to clinical practice, investigations, and therapeutic management of patients with ocular inflammatory diseases and complex uveitic conditions, with an in-depth discussion surrounding the diagnosis and therapeutic strategies of specific inflammatory disorders.
Treatment of Sjogren’s Syndrome dry eye in mouse model
Sjogren’s syndrome (SS) is a chronic autoimmune disease characterised by inflammation of the exocrine glands, specifically the salivary and lacrimal glands that produce saliva and tears, respectively. The immune-mediated attack on the salivary and lacrimal glands leads to the development...Principles of management
Whatever section of pathology is to blame and wherever it strikes, the aim of treatment is always the same. Find the cause if you can. Establish the effects of the cause. Halt the pathological process if you can. Reverse its...Acute dacryoadenitis secondary to COVID-19
Acute dacryoadenitis is defined as the rapid onset of discomfort and swelling of the lacrimal gland, classically giving rise to an S-shaped ptosis [1]. Dacryoadenitis is the most common cause of a painful mass in the lacrimal gland in young...
Effects of market competition on the price of topical eye drops in the US
The authors retrospectively examined the relationship between the number of Federal Drug Administration (FDA)-approved manufacturers and the price change of generic and branded topical eye medications based on the formulations listed in the FDA Orange Book and the National Average...
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...
Implantation of intraocular pressure sensor in glaucoma patients
The authors report safety and accuracy of an intraocular intraocular pressure (IOP) sensor placed in the ciliary sulcus during planned cataract surgery. Six patients underwent implantation of the device; a silicone rubber ring-shaped device encapsulating pressure sensitive capacitors and a...
Undetected retinoblastoma management following vitrectomy
This retrospective study from a single-centre referral university hospital in Germany analysed data collected between 1991-2019 to comment on management and complications of undetected retinoblastoma eyes following vitrectomy. The 10 patients included had a mean age of 36.1 months (range...
