You searched for "nAMD"
Exposure to atomic bomb radiation and age-related macular degeneration in later life
1 October 2015
| Wai Siene Ng
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Retina / Uvea / Vitreous
This paper is one of the outcomes of the Adult Health Study; a cohort study of the atomic bomb survivors of Hiroshima-Nagasaki in Japan. It investigates the proposed association between pasty radiation exposure early in life and the presence of...
My top five: Innovative approaches to dry AMD
2 February 2024
| Nikhil Sharma
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AMD
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...
My Top Five: Innovative approaches to dry AMD
2 February 2024
| Nikhil Sharma
|
AMD
Age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness in the developing world with its prevalence rising alongside age. In societies characterised by ageing populations, it is imperative we explore more effective treatment to alleviate the...
General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology
2 August 2024
| Arun James Thirunavukarasu
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Ophthalmology
Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...
Is an increased homocysteine level associated with greater risk of AMD?
1 June 2015
| Jonathan CP Roos
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Retina / Uvea / Vitreous
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Age-related macular degeneration, Women's Health Study, homocysteine, prospective cohort, risk factor
Basic research studies have implicated homocysteine in causing vascular endothelial dysfunction and inflammation, and this has been borne out in large observational studies which suggested that elevated homocysteine is associated with increased risk of cardiovascular disease. In order to determine...
Macular pigment in relatives of AMD patients
3 April 2024
| Kurt Spiteri Cornish
|
Retina / Uvea / Vitreous
Blue light causes photo-oxidative retinal injury and macular pigment (MP), with lutein, zeaxanthin and mesozeaxanthin as the main components, as a filter that protects the macula from this damage. Previous studies indicated that low levels of macular pigment optical density...
The long-term effects of AREDS on AMD progression
1 December 2013
| Brian Ang
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Retina / Uvea / Vitreous
The Age-Related Eye Disease Study (AREDS) was an 11-centre, double-masked, clinical trial that in 2001 found a high-dose of antioxidant vitamins plus zinc was effective in protecting against progression of age-related macular degeneration (AMD) in patients with moderate to high...
Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress
2 August 2024
| Rod McNeil
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Ophthalmology
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...
Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device
1 December 2021
| Ibrar Ahmed, Panayiotis Maghsoudlou, Hani Hasan, Allaaeldin Abumattar, Nimish Shah
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Optometry, EYE - Vitreo-Retinal
Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...
CD40L activation of human RPE cells
1 August 2018
| Graham Wallace
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Retina / Uvea / Vitreous
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AMD, Age-related macular degeneration, CD40L, IL-1β, Inflammasome, MCP-1, RPE, Retinal pigment epithelium
Age-related macular degeneration (AMD) is the leading cause of reduced visual acuity in the elderly worldwide. The risk factors involved in AMD include smoking and diet, while genetics have been shown to have a significant role. Recently a link between...
2024
1 April 2024
| Baljean Dhillon (Prof), David Lockington
Welcome to our Spring Special of 2024! The year is well underway and I can feel change is in the air. It’s the Chinese year of the dragon, generally regarded as a good sign, plus it’s 40 years on from...
Control of bleeding with diabetic vitrectomy under air
1 August 2019
| Kurt Spiteri Cornish
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Retina / Uvea / Vitreous
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Air-perfused membrane dissection, fibrovascular membrane, proliferative diabetic retinopathy, vitrectomy
The authors describe a modified diabetic vitrectomy using continuous air infusion in diabetic eyes with severe fibrovascular proliferation. In their case series of 25 eyes (20 patients), intravitreal bevacizumab (1.25mg) was used one week prior to surgery. Fifteen eyes had...