You searched for "neovascular"
Retinal pigment epithelium tears
1 June 2016
| Sofia Rokerya
|
EYE - Vitreo-Retinal
In this paper the authors review the current knowledge of retinal pigment epithelium (RPE) tears. Although rare these can cause loss of visual acuity. They can occur spontaneously in pigment epithelial detachment (PED) due to occult choroidal neovascularisation (CNV), retinal...
OCTA FAZ measurements in vein occlusion
1 February 2018
| Saruban Pasu
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EYE - Vitreo-Retinal
Previous studies have confirmed that foveal avascular zone (FAZ) enlargement is correlated with visual acuity impairment in patients with retinal vein occlusion (RVO). This current study aimed to evaluate the OCT angiography parameters: the area of FAZ, foveal and parafoveal...
Short-term effects of intravitreal bevacizumab on the cornea
1 December 2014
| Khadijah Basheer
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EYE - Cornea, EYE - General
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anterior chamber depth, bevacizumab, central corneal thickness, intraocular pressure, iridocorneal angle, simulated keratometry
Bevacizumab has been extensively used to treat macula oedema and neovascularisation of the retina and it has also been useful in the management of corneal neovascular diseases. This prospective study aimed to provide more information on the effect bevacizumab may...
Ocular complications in retinal vasculitis
1 February 2018
| Efrosini Papagiannuli
|
EYE - Vitreo-Retinal
In this retrospective study the authors aimed to characterise the incidence rates of visual loss and ocular complications associated with retinal vasculitis (RV – annual incidence of 1-2/ 100000/ per annum). A secondary objective was to compare the visual outcomes...
Twenty-five years in retina
In the next of our articles celebrating 25 years of Eye News, the authors look at how the retina specialty has changed over this time and ask what the future might hold. Retinal disease management has benefited from great advances...Does vitrectomy increase the risk of glaucoma? A retrospective review from a UK hospital
5 April 2022
| Aiman Jamal, Helen Burn, Asifa Shaikh
|
EYE - Glaucoma, EYE - Vitreo-Retinal, EYE - General
The authors investigate what proportion of patients undergoing pars plana vitrectomy subsequently developed ocular hypertension or a diagnosis of glaucoma. A systematic review carried out in 2017 including seven studies found that there is evidence that pars plana vitrectomy (PPV)...
Brolucizumab in age-related macular degeneration, HAWK Study
3 October 2023
| Kurt Spiteri Cornish
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EYE - Vitreo-Retinal
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Neovascular age-related macular degeneration, aflibercept, anti-vascular endothelial growth factor therapy, brolucizumab, commercial formulation
The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...
A new observation point: updating the nomenclature and classification with OCT
The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...Broadening of treatment options for potentially blinding retinal conditions
2 August 2022
| Rod McNeil
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EYE - General
Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...
Surgical effect of limited membrane dissection
1 October 2017
| Fiona Rowe (Prof)
|
Paediatric Ophthalmology / Strabismus
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Minimally invasive, strabismus surgery, tenon capsule
Strabismus surgery was performed with minimal dissection of Tenons sheath and minimal tissue manipulation compared to conventional methods for patients with pure horizontal strabismus – to evaluate the effect on surgical outcomes. The study included 54 patients; 52% female. Mean...
Clinical predictors of proliferative sickle cell retinopathy
29 March 2024
| Kurt Spiteri Cornish
|
EYE - Vitreo-Retinal
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
MicroRNA inhibits corneal neovascularisation
1 August 2018
| Graham Wallace
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EYE - Cornea, EYE - General
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Biomechanical stress, Corneal epithelium, MicroRNA-204, Neovascularization, VEGF, VEGFR2
MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...
