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Ophthalmic presentations and outcomes in Erdheim-Chester disease

This is a comprehensive article describing clinical manifestations and pathogenesis of Erdheim-Chester disease (ECD) followed by a literature review of the available treatments. The authors look to compare historical treatment (HT) with vemurafenib, a BRAF inhibitor. ECD is a non-Langerhans...

Colour Doppler imaging before and after orbital decompression in thyroid eye disease

In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...

IgG4 related orbital disease

This retrospective study was done to determine the prevalence of IgG4 related orbital disease (IgG4ROD) in patients who previously had biopsies for suspected idiopathic orbital inflammatory disease (IOID) and / or orbital lymphoproliferative disease (OLD). The charts and slides of...

Orbital rhabdomyosarcoma treatment characteristics

The aim of this study was to review the clinical presentation, management, local and systemic outcomes of 14 orbital rhabdomyosarcoma (OR) cases with the focus on the role of surgery as treatment. The mean age at presentation was eight years...

Silicone oil migration presenting as an eyelid cyst

The author presents a single case report of a rare complication of silicone oil tamponade, silicone oil migration, after pars plana vitrectomy. A seven-year-old female, with a history of vitrectomy one year prior for penetrating eye trauma, presented with a...

Is exenteration helpful in invasive fungal sinusitis?

Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...

Orbital abscess following posterior subtenon steroid injection

The authors report a case of orbital cellulitis following posterior subtenon injection of triamcinolone acetonide. A 57-year-old male patient with a background of complicated cataract surgery underwent vitrectomy with explantation of dislocated intraocular lens and insertion of anterior chamber lens....

Retrobulbar amphotericin B for rhino-orbital-cerebral mucormycosis

Rhino-orbital-cerebral mucormycosis (ROCM) is a rare and often fatal infection usually occurring in immunocompromised patients from diseases such as diabetes, haematological malignancy and solid organ transplantation. Current standards of care include systemic antifungal therapy and debridement, including exenteration. This study...