You searched for "proptosis"
Clinical predictors of proliferative sickle cell retinopathy
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Orbital cellulitis - an overview of the diagnosis and management
Periorbital (preseptal) and orbital cellulitis are infections of the subcutaneous tissues of the eye. They are differentiated by the location of the infection. Periorbital cellulitis refers to infection of the eyelid and subcutaneous tissues anterior to the orbital septum, whereas...Aug/Sep 2016 Quiz
History A 45-year-old female patient presented with left upper eyelid swelling present for six months. There was mild pain and a sense of fullness over the left eye. Examination revealed a palpable firm mass over the lacrimal gland area without...
Orbital Schwannomas
This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...SAVE THE DATE - Optos Peer Discussion Webinar
‘Working with ultra-widefield multi-modality retinal imaging: the clinical and practical value this technology adds to your ophthalmology clinic.’OSCE Fair 2024
by Ping Hei Alfie Lee, Y5 Medical Student, Newcastle University, UK. OSCE stands for Objective Structured Clinical Examination. It consists of a series of simulated scenarios evaluating student’s clinical competencies based on a set of standardised scoring rubrics. In the...Trans-sinus endoscopic removal of retrobulbar air gun pellet within the orbital apex
Injuries to the eye have been widely reported in medical literature due to a variety of mechanisms causing significant morbidity and occasional unexpected mortality for the patient [1]. It is often wrongly assumed that air gun pellets lack this potential....Thyroid eye disease
Thyroid eye disease (TED) is an autoimmune condition with a spectrum of signs and symptoms, usually associated with Graves’ hyperthyroidism. The diagnosis is based on history and physical examination but there are further investigations that can aid diagnosis if unclear....
Prognostic factors for visual acuity in patients with LHON after gene therapy
This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...
Visual acuity conversion to digital acuity
The author proposes a basic set of evidence-based digital acuities for alpha vision to facilitate formatting of visual acuity data uniformly. This work was informed by a review of the literature. A full table provides US and international classification of...
