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903 results found

Implantation of intraocular pressure sensor in glaucoma patients

The authors report safety and accuracy of an intraocular intraocular pressure (IOP) sensor placed in the ciliary sulcus during planned cataract surgery. Six patients underwent implantation of the device; a silicone rubber ring-shaped device encapsulating pressure sensitive capacitors and a...

Visual recovery following Ex-Press vs. trab

The authors describe a prospective randomised study of 64 POAG subjects with controlled IOPs comparing visual acuity data in patients randomised to either Ex-Press model P50 or trabeculectomy. Visual acuities were recorded at baseline, day one, weeks one and two...

Ovarian hormones drive onset of Sjogren’s disease in mice

Sjogren’s syndrome (SS) is a debilitating, sight-threatening, systemic autoimmune disease with no effective treatment available. SS is characterised by lacrimal gland lymphocytic infiltration and epithelial cell death, as well as by the presence of serum autoantibodies. Patients have severe dry...

Adjunctive topical 5-FU vs. MMC for surgically excised, localised OSSN

Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive OSSN has been surgical excision with or without intraoperative cryotherapy. Postoperative adjunctive topical chemotherapy significantly...

Low dose steroids for ocular dry eye disease in graft vs. host disease

This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...

A review of chromosome 9p21 POAG susceptibility locus

Primary open angle glaucoma (POAG) is a genetically complex disease and the overall phenotype is influenced by multiple traits including intraocular pressure (IOP), central corneal thickness and structural features of the optic nerve head. Therefore, genes affecting any of these...

Prostaglandin levels in femto cataract surgery

Following previous reports of pupil size decrease after femtosecond treatment, the authors compare levels of prostaglandins in patients undergoing femtosecond assisted cataract surgery with those having routine cataract surgery. Patients with inflammatory eye disease, previous trauma surgery, age-related macular degeneration...

Low cost drainage device use in paediatric glaucoma

This is a prospective study from a tertiary referral centre from India of 34 eyes (31 patients) under 16 years with uncontrolled refractory glaucoma with medical treatment. A low cost glaucoma drainage device (GDD) – Aurolab aqueous drainage implant (ADDI),...

Mid-term evaluation of the new Glaukos iStent

This is a prospective non-randomised interventional study to assess the efficacy and safety of the Glaukos GTS-400 iStent combined with cataract surgery. The patients enrolled in the study had cataract and primary open angle glaucoma, pseudoexfoliation glaucoma or ocular hypertension....

Morning glory syndrome associated with PHPV

This is a retrospective review of the medical records of 85 eyes / 74 patients diagnosed as morning glory syndrome (MGS) in the clinic between November 2009 and November 2012. Twenty two eyes of 19 patients diagnosed as having MGS...

Secondary intraocular lens implantation in children

This is a retrospective study of the medical records of children under the age of 16 who underwent secondary lens implantation for aphakic corrections after previous congenital cataract surgery over a period between January 2000 and December 2010. The study...

Mitomycin C versus 5-FU as an adjunctive treatment for trabeculectomy

Antifibrotic agents are used during trabeculectomy (TRAB) to improve long-term surgical success by reducing fibrosis of subconjunctival and episcleral tissue. The purpose of this meta-analysis was to directly compare the efficacy and safety of the two most frequently used antifibrotic...