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1757 results found

Clinical features of ocular syphilis

The study looked at 24 patients (20 males, four females) with serological evidence of syphilitic infection who presented to a tertiary ophthalmic centre. Ocular involvement was the first manifestation of syphilitic disease in 96% and Human Immunodeficiency Virus (HIV) seropositivity...

Prediction of visual outcome in IIH

In this prospective study, visual outcome of 40 patients with idiopathic intracranial hypertension (IIH) was compared with clinical and neuro-ophthalmic parameters. The purpose of this was to determine any correlation to try and predict visual outcome for IIH patients. Parameters...

Is exenteration helpful in invasive fungal sinusitis?

Invasive fungal sinusitis is a potentially lethal disease that causes painful orbital apex syndrome with ophthalmoplegia and visual loss. The mechanism of ophthalmoplegia and visual loss is not clear, and neither is the role of radical surgery-orbital exenteration. The authors...

Outcomes of adult new-onset strabismus presenting acutely

This study evaluated causes, neuroimaging rates and results, and clinical courses of adults presenting to an ophthalmology emergency department with diagnosis of new-onset strabismus. This was a retrospective study of 557 adults (54.8% male) with mean age of 57.3 ±16.7...

Iranian prevalence of amblyopia

This population-based study was conducted in the Mashhad County in the north east of Iran to determine the prevalence of amblyopia and its determinants and to predict the health needs of the county. This was a cross-sectional study and of...

Effects of blood donation on the physiology of the eye

Hypovolaemia is a state of decreased blood volume, the reduction of which reduces tissue perfusion which may in turn lead to cellular hypoxia and end-organ damage. In blood donation, 500ml of blood is collected in ten minutes. This equates to...

Is laser refractive surgery safe for patients taking isotretinoin?

This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...

BCLA webinar will look at medical uses for contact lenses

A BCLA webinar will review the various indications for medical use of contact lenses and how different lens modalities work.

Effective treatment for rare sight-threatening infection

A drug candidate, based on pioneering UCL and Moorfields Eye Hospital research and currently under development by SIFI S.p.A., has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

OCT imaging of occluded puncta

This is a description of the use of enhanced depth optical coherence tomography (OCT) to see whether a patent ampulla or canaliculus is detectable in patients with absent or occluded puncta. Nine occluded puncta of six patients with epiphora were...

ABCA1 mediates lipid efflux in the retina

Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. There are two forms of AMD, dry and wet, the latter so named because of the presence of choroidal neovascularisation. Both forms lead to retinal pigment...