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Retinopathy of prematurity treatment in the South West of England: long-term outcomes 1997-2008
Retinopathy of prematurity (ROP) is a condition that affects the developing retinal vascular system of pre-term babies. If left untreated, ROP can lead to severe visual impairment. The severe visual impairment caused by untreated ROP can be prevented by screening...
Validity of coding in neuro-ophthalmology within large administrative datasets
A systematic review of validation studies of the International Classification of Disease (ICD) coding system, ICD-9 and ICD-10 is presented by the authors. Three searches were conducted based on three concepts, firstly health administration claims and ICD codes, secondly diagnostic...
Association between serum 25-hydroxyvitamin D levels and age-related cataracts
Cataractogenesis occurs as a result of ageing, smoking, exposure to UV radiation and genetic predisposition. Antioxidants can reduce the cataract risk as found in animal models and humans and vitamin D is one of them. This epidemiological study based in...Strabismus in thyroid eye disease
Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...Implementing technology to improve global eye health
Technological innovation is providing new solutions to transform global eye health [1–5]. In particular, research towards the development of artificial intelligence (AI) tools in ophthalmology has gained pace in recent years. However, there has been little research relating to its...Sustainability in ophthalmology and healthcare: An overview
Finally, even staunch sceptics are coming around to recognising that climate change is real and that we should do something about it. But how proximal the threat is and at what pace change has to happen is not universally agreed...OOC (Oxford Ophthalmological Congress) 2024
by Samuel Verdin, Editorial Coordinator, Eye News. We were recently ‘daan saaf’ in England for the wonderfully scientific and long-standing Oxford Ophthalmological Congress for their 107th year! Founding in 1909 by Robert W Doyne, the congress is guided by the...Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service
The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...The role of inflammation in the pathophysiology of DMO
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...
RCT of operative routes for congenital cataract surgery
The authors evaluated the performance of 25G vitrectomy systems in the management of congenital cataract in infants through two routes – anterior (transcorneal) and posterior (pars plana). This was a prospective randomised trial (RCT) of 24 eyes of 12 patients...
Fibrosis treated with amniotic membrane
In this paper, the authors describe the surgical management of complex strabismus using amniotic membrane grafts in six patients with complex, repeat previous strabismus surgery and two patients with periocular surgery. Frozen amniotic membrane allograft was used. The study had...
